CORE--TISSUE RESEARCH AND PATHOLGOGY SERVICES

核心——组织研究和病理学服务

• 批准号: 6989547
• 负责人: RAJIV DHIR
• 金额: $ 8.35万
• 依托单位: UNIVERSITY OF PITTSBURGH AT PITTSBURGH
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-09-22 至 2009-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6989547
• 关键词: biomedical facility; clinical research; histology; histopathology; human data; neoplasm /cancer; neoplastic process; tissue /cell preparation

The Tissue and Research Pathology Services (TARPS) is a newly proposed shared facility that serves as the central support for UPCI research programs needing tissue materials from patients at the University of Pittsburgh Medical Center (UPMC). The main objectives of TARPS are (1) to provide a mechanism to simplify and streamline the process of research tissue accrual and disbursement and (2) to provide efficient research pathology support services. The tissue accrual and disbursement function of TARPS has been in existence since 1991 as a small service facility, with a focus on genitourinary cancers. The resource has substantially expanded in the last 5 years and now procures and disburses tissue materials from patients with a diverse array of cancers, and provides support to major research projects such as the hmg Specialized Program Of Research Excellence (SPORE), Early Disease Research Network (EDRN)-related research efforts, and several other cancer research programs. Services provided by TARPS include (1) tissue and biological specimen procurement services, (2) research histology services, (3) annotated clinical data, and (4) the Tissue Micro-Array (TMA) facilities. Future efforts include development of procedures to molecularly profile tumors on a real time basis. TARPS plans to extend the development of its infrastructure already in place for cancers such as prostate and head and neck cmacers, to other areas such as gastrointestinal and pancreatic cancers, hematologic malignancies, and melanoma.

组织和研究病理学服务（TARPS）是一个新提出的共享设施，是对需要匹兹堡大学医学中心（UPMC）患者组织材料的UPCI研究计划的中心支持。篷布的主要目标是（1）提供一种简化和简化研究组织应计和支出过程的机制，以及（2）提供有效的研究病理学支持服务。组织 自1991年以来，篷布的应计和支付功能一直存在为小型服务设施，重点是泌尿生殖器癌。在过去的5年中，该资源已大大扩展，现在从各种癌症群体中采购并发出组织材料，并为HMG HMG专业研究卓越计划（SPORE），早期疾病研究网络（EDRN）相关的主要研究项目提供支持，并提供支持。 研究工作以及其他一些癌症研究计划。 篷布提供的服务包括（1）组织和生物标本采购服务，（2）研究组织学服务，（3）注释的临床数据以及（4）组织微阵列（TMA）设施。未来的努力包括开发实时分子概述肿瘤的程序。 TARPS计划将其基础设施的发展扩展到癌症，例如前列腺和头颈部cmacers，到胃肠道和胰腺癌，血液学恶性肿瘤和黑色素瘤等其他地区。