Ecodevelopmental Classes of Youth Drug Use/Risky Sex

青少年吸毒/危险性行为的生态发展类别

• 批准号: 6876224
• 负责人: GUILLERMO PRADO
• 金额: $ 7.58万
• 依托单位: UNIVERSITY OF MIAMI SCHOOL OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-09-20 至 2005-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6876224
• 关键词: AIDS education /prevention; HIV infections; Hispanic Americans; adolescence (12-20); attitude; caregivers; clinical research; culture; disease /disorder classification; disease /disorder proneness /risk; drug abuse; drug abuse prevention; family structure /dynamics; high risk behavior /lifestyle; human data; human therapy evaluation; outcomes research; peer group; sex behavior; socioenvironment; substance abuse related behavior

DESCRIPTION (provided by applicant): The goal of the proposed study is to answer the question: "For which subgroups of Hispanic adolescents are specific drug use and HIV preventive interventions efficacious and for whom are they not?" This application proposes to answer this question by conducting secondary data analysis with this highly vulnerable population. The proposed study will be accomplished through two aims. AIM 1 is to identify classes of risk for this population. Classes of risk will be identified at baseline based on individual level variables (i.e., attitudes, beliefs, and intentions regarding drug use and sexual behavior) and ecodevelopmental variables (i.e., family functioning, parental monitoring of adolescent's peers, and the adolescent's orientation toward the American culture). AIM 1 will be tested by hierarchical cluster analyses and discrete latent mixtures. AIM 2 is to estimate the efficacy of the preventive interventions with respect to preventing drug use and unsafe sexual behavior across the classes of risk identified in Aim 1. Hierarchical Linear Modeling will be used to test AIM 2. Planned post-hoc analyses will be conducted to (a) explore the efficacy of the interventions within the classes identified and (b) the mechanisms that may mediate the effects of the intervention within each of the classes. Findings that intervention efficacy varies as a function of individual's class membership and that intervention efficacy is mediated by different variables within class will have implications for the development of a new generation of drug use and HIV preventive interventions for Hispanic adolescents. Specifically, the results of this study will help determine what specific ecodevelopmental and individual factors need to be targeted within different subgroups of Hispanic adolescents to maximize intervention efficacy/effectiveness in preventing drug use and HIV. This study has the potential to help reduce health disparities in Hispanic populations.

描述（由申请人提供）： 拟议研究的目的是回答以下问题：“特定吸毒和艾滋病毒预防干预措施对哪些西班牙裔青少年亚群有效，对哪些人无效？”该应用程序建议通过对这个高度脆弱的人群进行二次数据分析来回答这个问题。 拟议的研究将通过两个目标来完成。 目标 1 是确定该人群的风险类别。 将根据个人水平变量（即关于吸毒和性行为的态度、信仰和意图）和生态发展变量（即家庭功能、父母对青少年同龄人的监督以及青少年对青少年的同龄人的取向）在基线处确定风险类别。美国文化）。 AIM 1 将通过层次聚类分析和离散潜在混合物进行测试。 AIM 2 旨在评估目标 1 中确定的风险类别中预防吸毒和不安全性行为的预防干预措施的有效性。将使用分层线性模型来测试 AIM 2。将进行计划的事后分析(a) 探索已确定类别中干预措施的有效性，以及 (b) 可能调节每个类别中干预措施效果的机制。 干预效果随个人班级成员身份的变化而变化，并且干预效果由班级内的不同变量介导，这一发现将对西班牙裔青少年新一代吸毒和艾滋病毒预防干预措施的发展产生影响。 具体来说，这项研究的结果将有助于确定西班牙裔青少年不同亚群中需要针对哪些特定的生态发展和个人因素，以最大限度地提高预防吸毒和艾滋病毒的干预效果。 这项研究有可能帮助减少西班牙裔人口的健康差异。