PROCESSING AM SIGNALS IN AUDITORY SYSTEM

听觉系统中的中波信号处理

• 批准号: 6627885
• 负责人: GARY J ROSE
• 金额: $ 12.41万
• 依托单位: UNIVERSITY OF UTAH
• 依托单位国家: 美国
• 财政年份: 2000
• 资助国家: 美国
• 起止时间: 2000-02-01 至 2004-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6627885
• 关键词: Anura; animal communication behavior; auditory discrimination; auditory pathways; auditory stimulus; behavior test; behavioral /social science research tag; electrophysiology; inferior colliculus; loudness; neural information processing; sound frequency

DESCRIPTION: (Adapted from the Investigator's Abstract) The long-term objectives of this research program are to understand how temporal patterns in communication sounds are represented and processed in the central auditory system. Much of the information in communication signals, including human language, resides in their temporal structure. An understanding of how the temporal structure of sounds is represented and processed in the nervous system, therefore, is vital to understanding the neural bases of communication and communicative disorders. The research will be conducted on the auditory system of anurans because the temporal structure of their vocalizations has been shown to be important in their reproductive biology and behavioral studies can be conducted to delineate their temporal processing abilities. Presently, little is known concernng the neural mechanisms of temporal processing in the auditory system. At a basic level, the temporal structure of sound consists of how its amplitude and frequency changes, i.e., is modulated, over time. The specific goals of this research are to gain insight into how amplitude modulations are represeted in the brain and the transformations in these representations. In a number of vertebrate species, including mammals, there is a transformation from a periodicity coding of the rate of amplitude modulation to an AM filter representation; most neurons in the midbrain respond best over a particular range of AM rate, i.e., are band-pass. The mechanisms underlying this transformation are poorly understood. The specific experiments outlined in this research proposal are designed to test hypotheses concerning the generation of band-pass AM selectivity. The roles of recovery processes and temporal integration will be investigated. Other experiments should reveal whether an 'AM map' exists in the midbrain.

描述：（根据调查员的摘要改编）长期 该研究计划的目标是了解时间模式如何 通信声音在中央听觉中表示和处理 系统。通信信号中的许多信息，包括人类 语言，存在于其时间结构。了解如何 声音的时间结构是在神经上表示和处理的 因此，系统对于理解沟通的神经基础至关重要 和沟通障碍。该研究将在听觉上进行 Anurans系统，因为他们发声的时间结构 被证明在其生殖生物学和行为研究中很重要 可以进行描述其时间处理能力。 目前，众所周知，暂时的神经机制很少 在听觉系统中处理。在基本层面上， 声音包括其幅度和频率如何变化，即调制， 随着时间的推移。这项研究的具体目标是了解如何 振幅调制在大脑中代表和转换 这些表示。在包括哺乳动物在内的许多脊椎动物中， 从振幅速率的周期性编码进行了转换 调制对AM滤波器表示；中脑中的大多数神经元反应 在特定范围的AM速率（即，最佳）是频道。机制 这种转变的基础知之甚少。具体实验 本研究建议中概述的旨在检验有关的假设 频道AM选择性的产生。恢复过程的作用和 时间整合将进行研究。其他实验应揭示 中脑是否存在“ AM MAP”。