Reducing Type 2 Diabetes Risk in African-American Youth

降低非裔美国青年患 2 型糖尿病的风险

• 批准号: 6599770
• 负责人: DEBORAH BURNET
• 金额: $ 12.57万
• 依托单位: UNIVERSITY OF CHICAGO
• 依托单位国家: 美国
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-07-01 至 2008-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6599770
• 关键词: African American; adolescence (12-20); behavior therapy; behavioral /social science research tag; clinical research; diabetes risk; diet; disease /disorder prevention /control; exercise; family structure /dynamics; health behavior; health disparity; human subject; human therapy evaluation; middle childhood (6-11); noninsulin dependent diabetes mellitus; nutrition related tag; outcomes research; patient oriented research

DESCRIPTION (provided by applicant): Obesity is rising dramatically in young people, and with it the incidence of type 2 diabetes in young people is increasing. This trend is especially pronounced in minority populations, including African Americans and Hispanics. Healthy nutrition and exercise have been shown to prevent or delay the onset of type 2 diabetes in adults. Translating these findings to effectively address populations of minority youth will involve multi-disciplinary challenges; however, if we do not implement preventive measures, we face the specter of rising premature morbidity and mortality among the minority groups at highest risk for early type 2 diabetes. Similarly, outcomes for minority youth with established diabetes are poor, reflecting a complex interaction between medical and social factors. Analysis of current disparities can help us target secondary prevention efforts to decrease excess morbidity and mortality. Dr. Burnet is an internist and a pediatrician. She wants to build upon her clinical experience and develop the ability to decrease disparities in diabetes outcomes for African-American youth in Chicago. Dr. Burnet will need additional training and mentoring as she develops the ability to conduct research in this area. At the end of five years, she will have gained that additional training, participated in population-based studies analyzing outcomes for diabetic youth in Chicago, and implemented a risk-reduction program for African- American youth at high risk for diabetes. Programs to modify nutrition and lifestyle habits in youth have been shown to work best when they involve children and parents together. Interventions need to be culturally and age appropriate. Dr. Burnet's main research project will be a community-based, family oriented intensive nutrition and exercise intervention designed to decrease risk of type 2 diabetes in African-American youth. Her aim is to provide a creative, cost-effective program which can be replicated in varied settings, and which builds on prior work and the extensive resources available for diabetes research through the University of Chicago. Through this career development award, Dr. Burnet expects to become established as an independent researcher and a leader in the effort to decrease racial disparities in diabetes outcomes.

描述（由申请人提供）： 年轻人的肥胖率急剧上升，随之而来的是年轻人中 2 型糖尿病的发病率也在增加。这种趋势在少数族裔中尤其明显，包括非裔美国人和西班牙裔美国人。健康营养和运动已被证明可以预防或延缓成人 2 型糖尿病的发病。将这些发现转化为有效解决少数族裔青年群体问题将涉及多学科挑战；然而，如果我们不采取预防措施，我们将面临早期2型糖尿病风险最高的少数群体过早发病率和死亡率上升的担忧。同样，患有糖尿病的少数族裔青年的治疗结果也很差，反映出医疗和社会因素之间复杂的相互作用。对当前差异的分析可以帮助我们确定二级预防工作的目标，以降低过高的发病率和死亡率。 伯内特医生是一名内科医生和儿科医生。她希望利用自己的临床经验，培养减少芝加哥非裔美国青年糖尿病结局差异的能力。伯内特博士在培养在该领域进行研究的能力时将需要额外的培训和指导。五年后，她将获得额外的培训，参加以人群为基础的研究，分析芝加哥糖尿病青少年的结果，并为糖尿病高危的非洲裔美国青少年实施一项降低风险计划。事实证明，改变青少年营养和生活习惯的计划只有让儿童和家长共同参与才能发挥最佳效果。干预措施需要适合文化和年龄。 Burnet 博士的主要研究项目是一项以社区为基础、以家庭为导向的强化营养和运动干预措施，旨在降低非裔美国青年患 2 型糖尿病的风险。她的目标是提供一个创造性的、具有成本效益的计划，该计划可以在不同的环境中复制，并且建立在先前的工作和芝加哥大学可用于糖尿病研究的广泛资源的基础上。通过获得这一职业发展奖，伯内特博士希望成为一名独立研究员和努力减少糖尿病结果种族差异的领导者。