REACH-OUT CHICAGO CHILDREN"S DIABETES PREVENTION PROJECT

接触芝加哥儿童糖尿病预防项目

• 批准号: 6870820
• 负责人: DEBORAH BURNET
• 金额: $ 47.79万
• 依托单位: UNIVERSITY OF CHICAGO
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-09-30 至 2009-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6870820
• 关键词: African American; adolescence (12-20); behavioral /social science research tag; body physical activity; clinical research; developmental nutrition; disease /disorder prevention /control; health behavior; health education; health service demonstration project; health services research tag; human subject; middle childhood (6-11); noninsulin dependent diabetes mellitus; nutrition related tag; obesity; outcomes research; parent offspring interaction

DESCRIPTION (provided by applicant): The association between obesity and the development of type 2 diabetes mellitus is well documented from physiological and epidemiological studies. As overweight is on the rise in the pediatric population due to high fat, low fiber diets and decreased physical activity, type 2 diabetes is becoming more prevalent in young people, especially among minority youth. As shown in the adult Diabetes Prevention Program, healthy nutrition and exercise habits and weight loss can effectively decrease the risk of type 2 diabetes. In pediatrics, programs to modify nutrition and lifestyle habits in order to decrease overweight have been shown to work best when they involve children and parents (or grandparents) together. These interventions need to be culturally and age appropriate. The proposed REACH-OUT Chicago Children's Diabetes Prevention Project is a community-based, family-oriented health program, grounded in behavioral theory and supported by empirical data, to decrease overweight and risk of type 2 diabetes in young people from the high risk, mainly African American population served by and surrounding The University of Chicago. The intervention was developed and pilot tested using insights from formative research within this community, so as to be culturally appropriate. Our specific aims are: (1) To test a culturally sensitive, community-based, family oriented intervention to decrease obesity and risk of type 2 diabetes in a high risk inner-city African American population using outcomes that measure body habitus, biochemical markers of insulin sensitivity, and measures of lifestyle habits, and (2) To evaluate the within-trial cost-effectiveness of this program, from the health system perspective. This program of translational research is designed through multidisciplinary collaboration within The University of Chicago and within the community we serve and is designed to address the needs of children and families within the cultural context of our community.

描述（由申请人提供）： 生理学和流行病学研究充分证明了肥胖与 2 型糖尿病发展之间的关联。由于高脂肪、低纤维饮食和体力活动减少，导致儿童超重的人数不断增加，2 型糖尿病在年轻人中变得越来越普遍，尤其是在少数族裔年轻人中。正如成人糖尿病预防计划所示，健康的营养和运动习惯以及减肥可以有效降低患2型糖尿病的风险。在儿科领域，事实证明，改变营养和生活习惯以减少超重的计划在儿童和父母（或祖父母）一起参与时效果最佳。这些干预措施需要适合文化和年龄。拟议的 REACH-OUT 芝加哥儿童糖尿病预防项目是一项以社区为基础、以家庭为导向的健康计划，以行为理论为基础并以实证数据为支持，旨在降低青少年超重和 2 型糖尿病高危人群的风险，主要是芝加哥大学及其周边地区的非裔美国人人口。该干预措施的制定和试点测试利用了该社区内形成性研究的见解，以适应文化。我们的具体目标是：（1）测试一种文化敏感、以社区为基础、以家庭为导向的干预措施，以降低高风险内城区非裔美国人的肥胖和 2 型糖尿病风险，使用测量身体习惯、生化标志物的结果。胰岛素敏感性和生活习惯测量，以及 (2) 从卫生系统的角度评估该计划的试验内成本效益。该转化研究计划是通过芝加哥大学和我们服务的社区内的多学科合作设计的，旨在满足我们社区文化背景下儿童和家庭的需求。