SUMMER RESEARCH EXPERIENCES FOR UNDERGRADUATES

本科生暑期研究经历

• 批准号: 6636573
• 负责人: Frank C Yin
• 金额: $ 8.82万
• 依托单位: WASHINGTON UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-03-01 至 2005-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6636573
• 关键词: health science research potential; science education; training; university student

DESCRIPTION (taken from application): This proposal is to support 10 undergraduate students with backgrounds in the physical sciences or engineering for summer research training in laboratories of Washington University faculty engaged in biomedical research. A salary of $4750 is requested for each student for a 10-week summer work experience. Participants will have the opportunity to be trained in and conduct research with biomedical researchers in active, well-funded laboratories. The mentors comprise more than a dozen, mostly senior, faculty who have extensive experience and proven track records mentoring undergraduates. In addition, almost all of the mentors' current or proposed projects have aspects that combine an aspect of physical science, engineering or computing to a biomedical research problem. Areas of research include cardiovascular mechanics, cell-cell interactions, protein folding, DNA sequence patterns, cell mechanics, oxidation of DNA by white cells, delivery of biological agents, regulation of stem cell differentiation, analysis of plant-pathogen interactions, structural aspects of enzymology, developing a coronary artery phantom for MR/imaging, mathematical modeling of electrical propagation in cardiac tissue, how proteins bind to DNA to regulate gene expression and the mechanics of cardiac looping. In addition to their research projects, students will spend an initial week getting an intensive introduction to biology, laboratory methods, biomedical ethics and laboratory safety. They will also participate in weekly faculty seminars, organize and run their own journal club, present their findings at a wrap-up symposium and attend similar presentations of other on-campus summer students. A few social activities will also be organized. The overall goal is to provide a meaningful, in-depth exposure to biomedical research for students whose backgrounds or majors might not otherwise provide such opportunities.

描述（取自应用程序）：该建议是支持10 具有物理科学或工程背景的本科生 在华盛顿大学教师实验室的夏季研究培训 从事生物医学研究。每个学生要求薪水为4750美元 为期10周的夏季工作经验。参与者将有机会 接受活跃的生物医学研究人员接受培训和进行研究 资金充足的实验室。导师组成了十几个，主要是 具有丰富经验和经过验证的记录的高级教师 指导本科生。此外，几乎所有导师的当前或 拟议的项目具有结合物理科学方面的各个方面， 工程或计算生物医学研究问题。研究领域 包括心血管力学，细胞 - 细胞相互作用，蛋白质折叠，DNA 序列模式，细胞力学，白细胞对DNA的氧化，递送 生物学剂，调节干细胞分化，分析 植物病原体相互作用，酶学的结构方面，发展 用于MR/成像的冠状动脉幻影，电气的数学建模 心脏组织中的传播，蛋白质如何与DNA结合以调节基因 表达和心脏循环的力学。除了他们的研究 项目，学生将花费最初的一周进行密集的介绍 用于生物学，实验室方法，生物医学伦理和实验室安全。他们 还将参加每周的教师研讨会，组织和运行 期刊俱乐部，在总结研讨会上介绍他们的发现，并参加类似的发现 其他校园夏季学生的演讲。一些社交活动将 也有组织。总体目标是提供有意义的，深入的 暴露于背景或专业的学生的生物医学研究 否则不能提供这样的机会。