CORE--PROTEIN CHEMISTRY

核心--蛋白质化学

• 批准号: 6576208
• 负责人: F PETER Guengerich
• 金额: $ 17.41万
• 依托单位: VANDERBILT UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-04-01 至 2003-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6576208
• 关键词: aminoacid analyzer; biomedical facility; computer assisted sequence analysis; environmental toxicology; high performance liquid chromatography; human tissue; protein sequence; tissue resource /registry; toxin metabolism

The Protein Chemistry Facility Core, directed by Dr. Guengerich (5% effort), provides amino acid sequence analysis and quantitative amino acid analyses. The EHS Center is only one of several sponsors of this facility and the Center?s usage accounts for approximately 28% of the facilities activity. The Center is asked to support Dr. Guengerich?s oversight in years 3-5, 50% of a Research Assistant and 25% of maintenance contracts for the LF3400t and AB Procise sequencer. This will allow Center investigators to use this facility at 50% of the actual cost. This facility has been used by nine investigators and extensive support has been provided to seven Center investigators from three Research Cores (Enzymatic Oxidation and Conjugation, Oxidative Damage, and Regulation of Gene Expression.

蛋白质化学设施核心，由 Guengerich 博士指导 （5%的努力），提供氨基酸序列分析和定量氨基酸 分析。 EHS 中心只是该设施的几个赞助商之一， 该中心的使用量约占设施活动的 28%。 该中心被要求支持 Guengerich 博士在第 3-5 年的监督，50% 一名研究助理以及 LF3400t 和 AB 25% 的维护合同 精确的测序仪。这将允许中心调查员使用该设施 按实际费用的50%。该设施已被九名调查员使用过 并向来自以下国家的七名中心调查员提供了广泛的支持： 三个研究核心（酶促氧化和结合、氧化损伤、 和基因表达的调节。