Summer Research and Training Program in Environmental Health Sciences

环境健康科学夏季研究和培训计划

• 批准号: 7783764
• 负责人: F PETER Guengerich
• 金额: $ 1.18万
• 依托单位: VANDERBILT UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-04-08 至 2013-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7783764
• 关键词: Antioxidants; Applications Grants; Area; Biological; Biomedical Research; Chemical Agents; Chemicals; Clinical Research; Coupled; DNA; Development; Discipline; Doctor of Medicine; Environmental Health; Enzymes; Event; Faculty; Funding; Genetic; Intervention; Investigation; Kidney; Manganese; Medical Students; Mentors; Mercury; Metals; Neurologic; Nitrogen; Oxygen; Participant; Physicians; Research; Research Personnel; Research Project Grants; Research Training; Role; Scientist; Signal Pathway; Structure-Activity Relationship; Students; Training Programs; Training and Infrastructure; Universities; career; cell injury; design; experience; improved; medical schools; member; patient oriented research; planetary Atmosphere; pre-doctoral; programs; research facility; response

DESCRIPTION (provided by applicant) This T35 grant application is designed to support medical students involved in a Summer Research and Training Program in Environmental Health Sciences. The proposed program will capitalize on the outstanding research facilities at the Vanderbilt University, School of Medicine, strengths in environmental health coupled with patient-oriented research, existing research and training infrastructure, and a demonstrated institutional commitment to the continued development of biomedical research and training. Funds are requested to support ten pre-doctoral short-term trainees per year (M.D. candidates). The list of preceptors includes twenty-eight faculty members representing basic and clinical research disciplines. Students will have the opportunity to participate in research projects in a variety of areas including mechanisms of cell damage by reactive oxygen and nitrogen species, biological intervention by antioxidants, chemical damage to DNA and genetic stability, signaling pathways induced as a response to genetic damage, structure-function relationships in mutagenic events, roles of enzymes in influencing damage from chemical agents, and mechanisms of neurological and renal damage induced by metals (especially manganese and mercury). The primary objective of this program is to provide a meaningful research experience in the field of environmental health sciences to medical students early in their academic careers and encourage more towards careers as physician-scientists. To achieve this objective, the program aims to 1) provide the medical student with the opportunity to conduct mentor-guided research in order to gain an improved understanding of biomedical research and career opportunities in the field; 2) provide students with information about what is involved in a career in biomedical investigation; 3) provide an atmosphere that encourages and facilitates student interaction with a diverse group of established investigators and clinicians in the broad area of environmental health sciences; and, 4) give participants a comprehensive and current overview of environmental health sciences and unsolved research problems in the field.

描述（由申请人提供） 该T35赠款申请旨在支持参与环境健康科学夏季研究和培训计划的医学生。 拟议的计划将利用范德比尔特大学的杰出研究机构，医学院，环境健康的优势以及面向患者的研究，现有的研究和培训基础设施，以及对生物医学研究和培训的持续发展的机构承诺。 要求资金每年支持十名博士后短期学员（M.D.候选人）。 主持人的清单包括代表基本和临床研究学科的二十8名教职员工。 Students will have the opportunity to participate in research projects in a variety of areas including mechanisms of cell damage by reactive oxygen and nitrogen species, biological intervention by antioxidants, chemical damage to DNA and genetic stability, signaling pathways induced as a response to genetic damage, structure-function relationships in mutagenic events, roles of enzymes in influencing damage from chemical agents, and mechanisms of neurological and renal damage induced by metals （尤其是锰和汞）。 该计划的主要目的是在学术职业的早期向医学生提供有意义的研究经验，并鼓励更多地作为医师科学家的职业。 为了实现这一目标，该计划的目的是1）为医学生提供有机会进行导师指导的研究，以提高对该领域生物医学研究和职业机会的了解； 2）为学生提供有关生物医学调查职业涉及的内容的信息； 3）提供一种鼓励和促进学生与各种各样的环境健康科学领域中既定的研究人员和临床医生群体的互动的氛围； 4）为参与者提供了对环境健康科学和该领域未解决的研究问题的全面概述。