CORE--BIOSTATISTICS

核心--生物统计学

• 批准号: 6565230
• 负责人: Donald W. Marion
• 金额: $ 20.73万
• 依托单位: UNIVERSITY OF PITTSBURGH AT PITTSBURGH
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-03-01 至 2003-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6565230
• 关键词: biomedical facility; brain injury; clinical research; data collection methodology /evaluation; epidemiology; human data; information systems; statistical service /center

The Administrative and Biostatistics Core is responsible for the coordination of all scientific, fiscal, educational, and quality control activities for the center. The administrative structure of the core includes an external monitoring committee that meets annually, an internal monitoring committee that meets quarterly, and a monthly meeting of the Center Director with all Primary Investigators. The monthly meetings have been held since 1991 and have been an excellent forum for the critical discussion of individual research projects, planning of future research, resolving budgetary issues, and integrating our clinical and basic science research efforts. The Core also is responsible for the national and international dissemination of our activities via the Brain Trauma Research Center Web Site. The Core will continue to coordinate productive collaborations of BTRC investigators with investigators in The Center for Injury Research and Control (Donald Marion, MD, Center Director), The Epidemiology Data Center (Seven Wisniewski, PhD), and The University of Pittsburgh Trauma Center (Andrew Peitzman, MD, Center Director), thereby facilitating the development of new avenues of research. We have found that such collaborative research can be accomplished with extraordinary efficiency because of the overlap of interests of the unfed investigators in these centers. An essential focus of this Core and of all the Center Investigators has been the conduct of high quality research leading to meaningful and statistically valid results. In the preparation of this program project we have placed particular emphasis on the biostatistical development and analysis of the data collected in the five primary projects Steen Wisniewski, PhD, Co-Director of this Core, has worked closely with each of the five primary investigators to guide the determination of sample sizes and advice on appropriateness of the specific statistical analyses proposed. He and his team at the Epidemiology Data Center will review all major scientific findings of our Center, and will edit all manuscripts for appropriateness of statistical analyses and conclusions prior to journal submission.

行政和生物统计学核心负责该中心的所有科学，财政，教育和质量控制活动的协调。核心的行政结构包括一个每年开会的外部监测委员会，一个每季度开会的内部监测委员会以及中心主任与所有主要调查人员举行的每月会议。自1991年以来，每月会议就一直举行，并且是对个别研究项目的批判性讨论，未来研究计划，解决预算问题以及整合我们的临床和基础科学研究工作的绝佳论坛。核心还负责通过大脑创伤研究中心网站对我们活动的国家和国际传播。核心将继续协调BTRC研究人员与伤害研究与控制中心（Donald Marion，MD，中心主任），流行病学数据中心（七个Wisniewski，PhD）和匹兹堡大学创伤中心（Andrew Peitzman，Andrew Peitzman，MD，MD，MD，MD，MD）的研究。我们发现，由于这些中心未成年研究者的利益重叠，因此可以通过非凡的效率来完成此类协作研究。该核心和所有中心研究人员的一个重要重点是进行高质量研究，从而导致有意义且统计上有效的结果。在准备该计划项目时，我们特别强调了对五个主要项目中收集的数据的生物统计学开发和分析，Steen Wisniewski，PhD，该核心的联合主任，与五名主要研究人员中的每个研究人员紧密合作，以指导确定样本量和建议针对特定统计分析的特定统计分析的建议。他和他在流行病学数据中心的团队将审查我们中心的所有主要科学发现，并将编辑所有手稿，以适当地提交期刊之前的统计分析和结论。