STEERABLE MICROFABRICATED MICROELECTRODE DRIVE

可操纵微加工微电极驱动器

• 批准号: 6394440
• 负责人: JITENDRAN MUTHUSWAMY
• 金额: $ 11.44万
• 依托单位: ARIZONA STATE UNIVERSITY-TEMPE CAMPUS
• 依托单位国家: 美国
• 财政年份: 2000
• 资助国家: 美国
• 起止时间: 2000-09-21 至 2004-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6394440
• 关键词: biomedical equipment development; brain electrical activity; electrical measurement; implant; medical implant science; microelectrodes; miniature biomedical equipment

DESCRIPTION:(adapted from applicant's abstract) The goal of this feasibility study is to develop a novel electrostatic microactuator technology for the purpose of implementing microelectrode arrays in a steerable configuration for recording extracellular potentials from populations of neurons. There is a need to develop a microelectrode positioning drive for precise placement and steering of electrodes in brain. It is expected that enabling researchers to independently steer and reposition chronically implanted microelectrode arrays in behaving animals will significantly advance neurophysiological research. The effort will develop the difficult microactuator technology that satisfies the displacement, force, stability, and precision requirements for microelectrode positioning in the brain and develop an integrated multi-channel microdrive system with its associated interconnects, signal and power delivery, and packaging requirements. The project should overcome a major technological barrier that heretofore blocked precision extracellular positioning and long-term recording with minimal hindrance from awake behaving subjects.

描述：（改编自申请人的摘要） 本可行性研究的目标是开发一种新型静电 用于实现微电极阵列的微致动器技术 在可操纵的配置中记录细胞外电位 神经元群体。需要开发微电极定位 驱动电极在大脑中的精确放置和操纵。预计 使研究人员能够长期独立地操纵和重新定位 在行为动物中植入微电极阵列将显着进步 神经生理学研究。努力将发展困难 满足位移、力、稳定性和 微电极在大脑中定位的精度要求并开发 集成的多通道微驱动系统及其相关 互连、信号和电力传输以及封装要求。这 项目应克服迄今为止阻碍的主要技术障碍 精确的细胞外定位和长期记录 来自清醒行为主体的障碍。