CHANGING EATING PATTERNS TO MEET LOW FAT GOALS: DISC

改变饮食模式以实现低脂肪目标：DISC

• 批准号: 6390757
• 负责人: LINDA Verner VAN HORN
• 金额: $ 5.66万
• 依托单位: NORTHWESTERN UNIVERSITY AT CHICAGO
• 依托单位国家: 美国
• 财政年份: 2000
• 资助国家: 美国
• 起止时间: 2000-04-01 至 2003-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6390757
• 关键词: behavioral /social science research tag; choice; clinical research; computer data analysis; dietary lipid; human data; middle childhood (6-11); nutrient requirement; nutrition related tag; saturated fat; self help

(Adapted from the applicant's abstract) The Dietary Intervention Study in Children (DISC) is an NHLBI-funded clinical trial designed to test the efficacy and safety of a dietary intervention to reduce serum cholesterol levels in 8-10 year-old pre-pubertal children with elevated LDL cholesterol levels. Children were randomized to intervention with a diet that was 28% of energy from total fat, less than 8% from saturated fat, up to 9% from polyunsaturated fat and less than 75mg/4200kJ cholesterol per day or usual care. Three 24-hour recalls were collected by nutritionists trained and certified in the Nutrient Data System of the Nutrition Coordinating Center. Foods were ranked by saturated fat and cholesterol content and classified as GO! and WHOA! foods to help with shopping and making appropriate choices when eating out. Families were educated regarding the types of foods that could be selected to help achieve the study goals, but a variety of individual adaptions occurred. After three years, the intervention group lowered mean dietary intake of total and saturated fat from a mean of 34% at baseline to 28.6%, and serum LDL-C was significantly lower than usual care by 0.09mmol/L (3.3mg/dL, p=.02). These data illustrate adaptation of dietary behavior to achieve the goal nutrient levels, but quantifying the specific changes in eating patterns, food choices and preparation techniques requires further programming and data analyses than what has been already accomplished in this study. Proposed are additional food group analyses to quantify and compare specific food choices adopted within and between groups. By utilizing the GO! vs. WHOA! system, the dietary data collected from over 6,000 recalls will be configured to identify lower vs. higher fat food choices across the overall eating pattern. This will permit better understanding about the self-selected dietary changes that were made in DISC among those children who adhered to the diet, document the level of nutrient adequacy achieved among this cohort and provide potential insights for future translational studies on reduced fat eating in this age group.

（改编自申请人的摘要） 儿童饮食干预研究（DISC）是NHLBI资助的临床 旨在测试饮食干预的功效和安全性的试验 降低8-10岁的前儿童的血清胆固醇水平 LDL胆固醇水平升高。 儿童被随机进行干预 饮食量是总脂肪的28％，饱和度不到8％ 脂肪，多不饱和脂肪最多9％，小于75mg/4200kJ胆固醇 每天或通常的护理。 营养学家收集了三个24小时的召回 在营养的营养数据系统中训练和认证 协调中心。 食物通过饱和脂肪和胆固醇进行排名 内容并归类为GO！还有哇！提供购物和制作的食物 外出就餐时的适当选择。 家庭接受了有关 可以选择以帮助实现学习目标的食物类型，但是 发生了各种各样的适应。 三年后，干预 组降低了平均脂肪和饱和脂肪的平均饮食摄入 基线时为34％，至28.6％，血清LDL-C明显低于平常 0.09mmol/L（3.3mg/dl，p = .02）护理。 这些数据说明了适应 饮食行为以达到目标营养水平，但量化 饮食方式，食物选择和准备技术的具体变化 需要进一步的编程和数据分析 在这项研究中完成。 提出的其他食品组分析 量化和比较组之间和之间采用的特定食物选择。 利用旅途！与哇！系统，从饮食数据中收集的饮食数据 6,000次召回将被配置为识别较低的脂肪食物选择 在整个饮食模式中。 这将使更好的理解 关于碟片中的自我选择的饮食变化 坚持饮食的孩子，记录营养充足的水平 在这个队列中实现并为未来提供潜在的见解 关于该年龄段脂肪饮食减少的翻译研究。