Neural correlates of cognitive biases in social phobia

社交恐惧症认知偏差的神经相关性

• 批准号: 7217000
• 负责人: Jason Scot Moser
• 金额: $ 2.96万
• 依托单位: UNIVERSITY OF DELAWARE
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-09-25 至 2008-09-24
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7217000
• 关键词: adolescence (12-20); behavioral /social science research tag; bias; choice; clinical research; cognition; emotions; evoked potentials; face expression; human subject; major depression; neural information processing; phobias; predoctoral investigator; psychological tests; psychomotor reaction time; psychopathology; psychophysiology; social adjustment; vocabulary; young adult human (21-34)

DESCRIPTION (provided by applicant): The long-term objective of the current research proposal is to provide a foundation of knowledge on the neural correlates of cognitive biases in social phobia in order to better inform clinically relevant issues such as nosology, diagnostics, treatment, and prevention. As a first major step towards achieving this long-term goal, the aims of the current study involve applying knowledge from experimental psychophysiology and cognitive science to the investigation of cognitive biases in adult psychopathology. Specifically, the current study aims are to utilize event-related brain potentials (ERPs) to examine cognitive biases implicated in the development and maintenance of social phobia and to identify those biases that are specific to social phobia (SP) by comparing them to those present in patients with major depressive disorder (MDD), as data suggest social anxiety and depression may manifest in similar ways, but the underlying cognitive mechanisms may be different. This will be accomplished by recording attentional allocation and response monitoring ERPs while patients with SP, patients with MDD and normal control participants perform two speeded reaction time tasks.

描述（由申请人提供）：当前的研究建议的长期目标是为社会恐惧症认知偏见的神经相关性提供知识的基础，以便更好地为临床相关的问题，例如疾病，诊断，治疗和预防。作为实现这一长期目标的第一步，当前研究的目的是将实验性心理生理学和认知科学的知识应用于对成人心理病理学认知偏见的研究。具体而言，当前的研究目的是利用与事件相关的大脑电位（ERP）来检查与社会恐惧症的发展和维持有关的认知偏见，并确定与社会恐惧症（SP）相比，通过与数据表明社交焦虑症（MDD）中存在的那些偏见（SP）可能相似，但在类似的方式中可能表现出不同的机制，但在类似的方式中表现出了不同的方式，而这些偏见可能是不同的，但可能是不同的。这将通过记录注意力分配和响应监测ERP来实现，而患有SP，MDD和正常对照参与者的患者执行了两项快速的反应时间任务。