ONTOGENY & FUNCTION OF PRIMATE VOCALIZATIONS

个体发育

• 批准号: 6311805
• 负责人: HAROLD T. GOUZOULES
• 金额: $ 3.85万
• 依托单位: EMORY UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1976
• 资助国家: 美国
• 起止时间: 1976-06-01 至 2001-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6311805
• 关键词: Mammalia; behavioral /social science research tag; congenital disorders; eye; growth /development; nervous system; psychology; vision

The overall goal of this project is to discover better ways to prevent and treat conditions that lead to blinding disorders in human children. We focus on neural and behavioral abnormalities associated with conditions such as congenital cataracts that occur during the neonatal period. During the past year we have continued to study abnormalities in motion processing, oculomotor behavior, and regulation of eye growth that occur following neonatal visual deprivation, but not during visual deprivation initiated somewhat later during postnatal development. These include abnormal growth of the eye leading to anisometropia, and asymmetrical responses to horizontal motion as assessed with visually evoked potentials and oculomotor measures. Monkeys reared under conditions of neonatal visual deprivation in previous years continue to be studied for the long-term presence of all of these disorders. Five new animals were reared under conditions of restricted binocular expo sure duri ng the past year, and those infants will be tested with ophthalmological, electrophysiological, psychophysical, and oculomotor methods during the coming year. FUNDING NIH EY05975 $166,645 7/1/95 - 6/30/00 PUBLICATIONS Boothe, R.G. and Fulton, A.B. Amblyopia. In Principles and Practice of Ophthalmology, 2nd Edition, D.M. Albert and F.A. Jakobiec (Eds.), W.B. Saunders Company, (In press). Bradley, D.V., Fernandes, A., Lynn, M., Tigges, M. and Boothe, R.G. Emmetropization in the rhesus monkey (Macaca mulatta) Birth to young adulthood. Invest. Ophthalmol. Vis. Sci. (In press). Bradley, D.V., Fernandes, A. and Boothe, R.G. The refractive development of untreated eyes of rhesus monkeys varies according to the treatment received by their fellow eyes. Vision Res. (In press). Brown, R.J., Wilson, J.R., Norcia, A.M. and Boothe, R.G. Development of directional motion symmetry in the monocular visually evoked potential of infant monkeys. Vision Res. 38:1253-1263, 1998. Wilson, J.R., Noyd, W.W., Aiyer, A.D., Norcia, A.M., Mustari, M.J. and Boothe, R.G. Asymmetric responses in cortical visually evoked potentials to motion are not derived from eye movements. Invest. Ophthalmol. Vis. Sci. (In press). P51RR00165-38 1/1/98 - 12/31/98 Yerkes Regional Primate Research Center

该项目的总体目标是发现更好的方法 预防和治疗导致人类盲目疾病的状况 孩子们。 我们专注于相关的神经和行为异常 在诸如先天性白内障等条件下发生的情况 新生儿期。 在过去的一年中，我们继续学习 运动处理，动眼行为和 调节新生儿视觉后发生的眼睛生长 剥夺，但在视觉剥夺期间没有剥夺有些剥夺 后来在产后发展。 这些包括异常生长 导致各种厌氧的眼睛，以及对 通过视觉诱发电位评估的水平运动， 眼动措施。 在新生儿条件下饲养的猴子 往年的视觉剥夺继续研究 所有这些疾病的长期存在。 五只新动物是 在受限制的双眼博览会条件下饲养 过去的一年，这些婴儿将接受眼科测试， 电生理学，心理物理和眼动方法 来年。 资金NIH EY05975 $ 166,645 7/1/95-6/30/00 出版物Boothe，R.G。和富尔顿，A.B。弱视。 在原则上 和眼科实践，第二版，D.M。阿尔伯特和F.A. Jakobiec（编辑），W.B。桑德斯公司（印刷中）。 布拉德利（D.V.） Fernandes，A.，Lynn，M.，Tigges，M。和Boothe，R.G。透气化 在恒河猴（Macaca Mulatta）中，成年。 投资。 眼科。 VIS。科学。 （在印刷中）。 布拉德利（D.V.），费尔南德斯（Fernandes）， A.和Boothe，R.G。未经处理的眼睛的折射 恒河猴根据其接受的治疗而有所不同 同伴的眼睛。 视觉res。 （在印刷中）。 布朗，R.J.，Wilson，J.R。， 诺西亚，上午和Boothe，R.G。定向运动的发展 单眼在视觉诱发的婴儿猴子的潜力中。 视觉res。 38：1253-1263，1998。Wilson，J.R.，Noyd，W.W。，Aiyer， A.D.，A.M.不对称 皮质视觉诱发运动潜力的反应不是 源自眼动。 投资。 眼科。 VIS。科学。 （在 按）。 P51RR00165-38 1/1/98-12/31/98 Yerkes地区灵长类 研究中心