MINORITY HIGH SCHOOL STUDENT RESEARCH APPRENTICE PROGRAM

少数民族高中生研究学徒计划

• 批准号: 3512797
• 负责人: LYNDA M FOX
• 金额: $ 1.5万
• 依托单位: ELEANOR ROOSEVELT INST FOR CANCER RES
• 依托单位国家: 美国
• 财政年份: 1988
• 资助国家: 美国
• 起止时间: 1988-03-01 至 1994-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3512797
• 关键词: minority institution research support; secondary schools

This proposal seeks support for a MicroVAX II and Evans and Sutherland PS300 graphics system to be located at the University City Sciene Center adjacent to the University of Pennsylvania. These instruments will provide major data processing and graphics capabilities for research projects directed by four investigators: N.R. Kallenbach, J. Leigh, S.W. Englander and B. Chance, focussing on molecular structure determination and dynamics of proteins and nucleic acids. Three areas will particularly benefit from the computer graphics facility: 1) structure determinations using high resolution 2D NMR techniques relying on distance-geometry algorithms; 2) EXAFS/XANES spectroscopy of metalloprotiens, and 3) simulation and interpretation of metal ion EPR and ESEEM spectra in enzyme substrate complexes. Together these projects place heavy emphasis on numerical data reduction, modeling and analysis. In addition the system will support software development and an EXAFS data bank made generally available through the National Biostructures Research Resource.

该建议寻求支持Microvax II和Evans以及 Sutherland PS300图形系统位于大学 宾夕法尼亚大学附近的城市科学中心。 这些仪器将提供主要的数据处理和图形 四个指导的研究项目的能力 调查人员：N.R。 Kallenbach，J。Leigh，S.W。英格兰和B. 机会，专注于分子结构的确定和 蛋白质和核酸的动力学。 将三个区域 特别受益于计算机图形设施：1） 使用高分辨率2D NMR技术进行结构测定 依靠距离几何算法； 2）EXAFS/XANES 金属孕剂的光谱和3）模拟和 酶中金属离子EPR和ESEEM光谱的解释 底物复合物。 这些项目在一起沉重 强调降低数值数据，建模和分析。 在 加法系统将支持软件开发和 EXAFS数据库通常通过国家提供 生物结构研究资源。