Target Of Rapamycin control of nutrient uptake.

雷帕霉素控制营养吸收的目标。

• 批准号: DP180101682
• 负责人: Prof Janni Petersen
• 金额: $ 27.23万
• 依托单位: Flinders University
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2018
• 资助国家: 澳大利亚
• 起止时间: 2018-03-01 至 2021-05-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP180101682
• 关键词: Target; Rapamycin; control; nutrient; uptake.

This project aims to study nutrient uptake in eukaryotes. It is expected to generate new knowledge of critical and conserved features of environmental and Target Of Rapamycin (TOR)-mediated control of nutrient uptake, specifically endocytosis, building on novel preliminary data that identifies novel TOR control points. The expected outcomes include new insights into mechanisms controlling nutrient uptake and fostering institutional collaboration. This knowledge is highly relevant to any industry or research project utilising living organisms, as nutrient availability supports survival, cell growth and proliferation.

该项目旨在研究真核生物中的养分吸收。预计它将产生有关雷帕霉素（TOR）介导的营养摄取的控制的关键和保守特征的新知识，尤其是内吞作用的控制，这是基于识别新型TOR控制点的新型初步数据的基础。预期的结果包括对控制养分吸收和促进机构合作的机制的新见解。由于养分可用性支持生存，细胞生长和增殖，因此这些知识与使用生物体的任何行业或研究项目高度相关。