FASEB RESEARCH CONFERENCE ON BIOLOGICAL METHYLATION

FASEB 生物甲基化研究会议

• 批准号: 2883854
• 负责人: JUDITH K CHRISTMAN
• 金额: $ 0.9万
• 依托单位: FEDERATION OF AMER SOC FOR EXPER BIOLOGY
• 依托单位国家: 美国
• 财政年份: 1999
• 资助国家: 美国
• 起止时间: 1999-07-16 至 2000-07-15
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2883854
• 关键词: DNA methylation; enzyme mechanism; enzyme structure; meeting /conference /symposium; methylation; methyltransferase; nucleic acid sequence; protein structure function; systematic biology; travel; workshop

This application is for partial funding for a conference called "Biological Methylation" to be held under the auspices of the Federation of American Societies for Experimental Biology (FASEB) at the Vermont Academy from July 16-July 22, 1999. This will be the fourth biennial FASEB conference on biological methylation. These meetings are virtually unique in their focus on the full range of AdoMet-dependent methyltransferases. Analysis of genomic sequences from archaea, eubacteria, fungi plants and animals suggests that a large fraction of all genes specify AdoMet dependent methyltransferases, yet it only a few years since it has been shown that most of these enzymes share a common core structure despite undetectable sequence identity. Thus, the meeting program is designed to promote a productive dialogue between scientists who study methyltransferase structure, function and regulation and those concentrating on biological importance of the effects of enzymatic methylation on a myriad substrates ranging from DNA, RNA and proteins to small organic molecules and metals. The conference will feature five speaker sessions (21 speakers), continual display of posters in a session lasting four days, and a series of 14 workshops on cutting-edge or controversial topics in the field that will include at least 30 min for open discussion. In addition, two workshops will be devoted to presentation and discussion of posters selected by the attendees as examples of the most exciting new work. This will be a new feature of this conference and should be a particularly good forum for younger investigators as well as new comers to the field to highlight their research findings. This series of conferences on biological methylation is a major meeting ground for discussion of DNA methylation and the DNA methylation society will continue to provide partial support for the registration fees of presenters of posters selected by its Board of Directors for special merit. Clinical and environmental applications of biological methylation, as well as basic research, will be highlighted at this conference. The ultimate goal of the organizers is to make sure that all participants have an equal opportunity to have their current research presented and discussed in a meaningful way, while continuing the tradition of providing expert overviews of new developments in important areas.

该申请是针对一个名为“生物甲基化”的会议的部分资金双年展FaseB生物甲基化会议。这些会议几乎是独一无二的，它们的重点是全范围依赖ADOMET的甲基转移酶。 分析来自古细菌，花生，真菌植物和动物的基因组序列，这表明所有基因的大部分都指定了依赖ADOMET的甲基转移酶，但仅几年以来，尽管已经证明，这些酶中的大多数具有共同的核心结构，尽管没有可检测到的核心结构身份。 因此，会议计划旨在促进研究甲基转移酶结构，功能和调节的科学家之间的富有成效的对话，以及那些专注于酶甲基化对从DNA，RNA，RNA和蛋白质到小有机分子以及小有机分子以及小有机分子以及小型有机分子以及小型底物的影响的生物学重要性的对话。金属。 该会议将举办五次演讲者会议（21个演讲者），在持续四天的会议中持续展示海报，以及一系列有关该领域尖端或有争议的主题的14个讲习班，其中至少包括30分钟进行公开讨论。 此外，两个研讨会将专门介绍和讨论与会者选择的海报，以此作为最令人兴奋的新作品的例子。 这将是本次会议的新功能，应该是一个特别好的论坛，对于年轻的调查员以及该领域的新来者，以突出他们的研究结果。 这一系列关于生物甲基化的会议是讨论DNA甲基化的主要见面，而DNA甲基化协会将继续为其董事会选择特殊优点选择的海报的演讲者的注册费提供部分支持。 在本次会议上，将强调生物甲基化以及基础研究的临床和环境应用。 组织者的最终目标是确保所有参与者都有一个平等的机会以有意义的方式介绍和讨论他们的当前研究，同时继续为重要领域的新发展提供专家概述的传统。