CORE--EXPERIMENTAL MICE

核心——实验小鼠

• 批准号: 6101962
• 负责人: CHARLES W TAYLOR
• 金额: $ 15.02万
• 依托单位: UNIVERSITY OF ARIZONA
• 依托单位国家: 美国
• 财政年份: 1999
• 资助国家: 美国
• 起止时间: 1999-07-01 至 2000-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6101962
• 关键词: SCID mouse; animal care; animal colony; athymic mouse; biomedical facility; laboratory mouse

The goal of the Experimental Mice Shared Service (EMSS) is to provide investigators at the Arizona Cancer Center with technical and scientific expertise in experimental mouse research with an emphasis on severe combined immune deficiency (scid) mouse models. Due to the need of investigations for experiments using other types of mice the service is expanding to include other mouse species (e.g. BALB/c, C3H, nude mice). The scid mice in the breeding colon and those scid mice used for experiments are separated with access to the breeding colony area being more restricted. All proposed mouse experiments/protocols are peer- reviewed by the Institutional Animal Care and Use Committee (IACUC). The IACUC consists of three community representatives, three laboratory veterinarians, one science librarian (non-scientific member), and 14 scientific peer researchers. The EMSS works in coordination with University Animal Control (UAC) and IACUC to provide quality veterinary care and prevention/detection of mouse diseases so that experiments can be completed in an efficient and scientifically sound manner.

实验性小鼠共享服务 (EMSS) 的目标是提供 亚利桑那州癌症中心的研究人员具有技术和科学 实验小鼠研究方面的专业知识，重点是严重的 联合免疫缺陷（scid）小鼠模型。由于需要 使用该服务的其他类型小鼠进行实验的调查 扩展到包括其他小鼠物种（例如 BALB/c、C3H、裸鼠）。 繁殖结肠中的 scid 小鼠和用于繁殖的 scid 小鼠 实验是分开的，可以进入繁殖区 更受限制。所有提议的小鼠实验/协议都是同行的 由机构动物护理和使用委员会 (IACUC) 审查。这 IACUC 由三名社区代表、三个实验室组成 兽医、一名科学图书馆员（非科学成员）和 14 名 科学同行研究人员。 EMSS 与 大学动物控制中心 (UAC) 和 IACUC 提供优质兽医服务 小鼠疾病的护理和预防/检测，以便实验能够进行 以高效且科学合理的方式完成。