NEURAL SIGNALS AT THE SPATIOTEMPORAL EDGE

时空边缘的神经信号

• 批准号: 2878899
• 负责人: Stephen Louis Macknik
• 金额: $ 3.67万
• 依托单位: HARVARD MEDICAL SCHOOL
• 依托单位国家: 美国
• 财政年份: 1999
• 资助国家: 美国
• 起止时间: 1999-03-01 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/2878899
• 关键词: Macaca mulatta; behavioral /social science research tag; lateral geniculate body; neural inhibition; neurophysiology; perceptual maskings; psychophysics; visual perception

This proposal outlines a single year of research to examine the strength of neural signals within the lateral geniculate nucleus of awake behaving primates, in response to spatiotemporal edges. Human psychophysical studies using illusions of invisibility (such as forward and backward masking) have shown that it is the edges of masks in space, as well as the timing of their onset and termination (their temporal edges), that are most effective in rendering targets invisible. Neural signals important to masking are therefore most likely to be associated with the mask s spatiotemporal edge. The proposed experiments will examine the neural correlates of these edge effects (both spatial and temporal) in the lateral geniculate nucleus of primates by recording from single-units while displaying stimuli used in previous human psychophysical experiments. These experiments will segregate the spatial edge effects from the temporal edge effects and test them conveyed separately. The results should reveal the relative strength of neural inhibition from the spatiotemporal edge of the mask in comparison with the signal generated in the mask s spatial and temporal interior.

该提议概述了一年的研究，以检查响应时空边缘的醒目醒目行为灵长类动物的侧向基因核中神经信号的强度。人类的心理物理研究使用隐形性幻觉（例如前向和向后掩盖）表明，它是空间中面具的边缘，以及它们的发作和终止时机（其时间边缘），在构成目标方面最有效。 因此，对掩盖重要的神经信号很可能与掩模的时空边缘有关。 提出的实验将通过记录单个单位记录的同时显示以前人类心理物理实验中使用的刺激，研究灵长类动物的侧向基因核中这些边缘效应（空间和时间上）的神经相关性。 这些实验将隔离时间边缘效应的空间边缘效应，并分别测试它们。 与掩模的空间和颞内部产生的信号相比，结果应揭示掩模时空边缘的神经抑制的相对强度。