ORAL MANIFESTATIONS OF HIV IN WOMEN

女性艾滋病毒的口腔表现

• 批准号: 2572396
• 负责人: M REDFORD
• 金额: --
• 依托单位: NATIONAL INSTITUTE OF DENTAL & CRANIOFACIAL RESEARCH
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/2572396
• 关键词: HIV infections; clinical research; data collection; dental disorder; dental disorder diagnosis; dental research; diagnosis design /evaluation; female; hormone regulation /control mechanism; human data; oral health; sign /symptom; women's health

Seemingly little attention had been paid to human immunodeficiency virus (HIV) infection in women. Much of what is currently known about HIV disease has been learned through the prospective study of large cohorts of gay men. Investigative efforts in the dental community have paralleled those in the general medical field. Most reports appearing in the dental scientific literature regarding the oral manifestations of HIV disease in women do not discuss how they relate to hormonal status and correlate with genital manifestations. Recognizing that the multisite Women's Interagency HIV Study (WIHS) is poised to break scientific ground relative to HIV infection in women, NIDR branch staff have taken the leadership role in developing an oral component that includes data collection about the oral manifestations of HIV disease in women, particularly as they relate to hormonal status and correlate with genital manifestations. Significant participation of the NIDR in this collaborative effort provides an efficient, cost-effective and timely means of targeting research towards several high-risk populations - women, minorities, and HIV infected individuals. Staff in the DPHPB is providing leadership for protocol design and conduct of the oral component. NIDR sponsored training for this study which was conducted in February, 1995. Baseline oral examinations began in April 1995, and were completed by June 1996. Second and third visit follow-up examinations are presently underway.

人类免疫缺陷似乎很少受到关注 女性感染病毒（HIV）。 目前已知的大部分内容 通过前瞻性研究了解了艾滋病毒疾病 一大群男同性恋者。 牙科领域的调查工作 社区与普通医学领域的情况相似。 最多 牙科科学文献中出现的有关 女性艾滋病毒疾病的口腔表现并未讨论她们如何 与荷尔蒙状态有关并与生殖器表现相关。 认识到多地点妇女机构间艾滋病毒研究 (WIHS) 准备在与艾滋病毒感染相关的科学领域取得突破 女性、NIDR 分支机构工作人员在以下方面发挥了领导作用： 开发一个口头部分，其中包括有关以下内容的数据收集 女性艾滋病毒疾病的口腔表现，特别是当她们 与荷尔蒙状态有关并与生殖器表现相关。 NIDR 大力参与这项合作工作 提供一种高效、经济且及时的目标定位方法 针对几个高危人群的研究——妇女、少数族裔、 和艾滋病毒感染者。 DPHPB 的工作人员正在提供 领导协议设计和口头部分的实施。 NIDR 赞助了本研究的培训，该培训于 1995 年 2 月。基线口试于 1995 年 4 月开始，并且 于 1996 年 6 月完成。第二次和第三次访问后续行动 目前正在进行考试。