11th International Conference on Cryptococcus and Cryptococcosis (ICCC)

第十一届隐球菌和隐球菌病国际会议（ICCC）

• 批准号: 10399173
• 负责人: David R Boulware
• 金额: $ 1.7万
• 依托单位: UNIVERSITY OF MINNESOTA
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-02-01 至 2023-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10399173
• 关键词: Acquired Immunodeficiency Syndrome; Adult; Affect; Africa; Africa South of the Sahara; African; Antifungal Agents; Antifungal Therapy; Archives; Area; Basic Science; Botswana; COVID-19 pandemic; Caring; Central Nervous System Infections; Cessation of life; Characteristics; Clinical; Clinical Investigator; Clinical Sciences; Clinical Trials; Collaborations; Communicable Diseases; Communities; Country; Cryptococcal Meningitis; Cryptococcosis; Cryptococcus; Cryptococcus neoformans; Disease; Etiology; Face; Failure; Family; Floor; Fostering; Funding; Future; Genome; Goals; Grant; HIV; HIV antiretroviral; Immune system; Immunity; Immunocompetent; Immunocompromised Host; Immunosuppression; Incidence; Income; International; International Aspects; Invaded; Knowledge; Medical; Meningitis; Microbiology; Minority; Molecular; Morbidity - disease rate; Mycoses; Opportunistic Infections; Oral; Participant; Pathogenesis; Pathogenicity; Patients; Persons; Postdoctoral Fellow; Predisposition; Prevention strategy; Program Development; Property; Request for Proposals; Research; Research Personnel; Resources; Retroviridae Infections; Risk; Scientific Advances and Accomplishments; Scientist; Sexual Reproduction; Signal Transduction; Site; South Africa; Structure; Students; The science of Mycology; Time; Translational Research; Travel; Twitter; Uganda; Underrepresented Minority; United States National Institutes of Health; Virulence; Wheelchairs; Woman; antiretroviral therapy; career; clinical practice; digital; fungus; graduate student; innovation; meetings; mortality; neglect; novel; pandemic disease; parity; pathogen; post-COVID-19; posters; preclinical development; programs; screening; social media; symposium; therapy development; tool; treatment strategy; vaccine development; web site; working group

ABSTRACT This proposal requests partial support for the 11th International Conference on Cryptococcus and Cryptococcosis (ICCC) to be held in Kampala, Uganda, January 10-14, 2022. Cryptococcosis accounts for 15% of AIDS-related deaths globally. Cryptococcal meningitis remains the most common neuroinfection among all adults in Sub-Saharan Africa and continues to be a major threat to a growing number of non-HIV immunocompromised persons. The broad and long-term goal of this ICCC is to bring together the world's leading researchers in this expanding field to foster cross-disciplinary discussions, research, and clinical collaborations to enhance our understanding of the mechanisms of Cryptococcus pathogenicity and best management of cryptococcosis. The specific aims of this meeting will be to convene leading experts whose expertise covers critical areas within this field, as well as early career and junior investigators, students, and postdocs. We anticipate hosting 300 participants. The program will be structured into 17 sessions covering the diverse properties and characteristics of the pathogen as well as host susceptibility and immunity, emphasizing what makes a normal host suddenly susceptible to this disease. Importantly, the conference will provide ample coverage of current and novel antifungals – ranging from pre-clinical development programs through ongoing/future clinical trials. Abstracts from junior investigators, graduate students, and postdoctoral fellows will be included among those selected for oral presentation. The conference will host two poster sessions which will permit all participants to actively contribute to these topics. Of the 17 session blocks, 12 blocks will be concurrent sessions to allow for smaller working groups to meet and more students / trainees to present their abstracts. The R13 resources will go towards supporting travel grant participation by graduate students and specifically under-represented minority scholars from US and Africa who present abstracts. We will seek parity with respect to women and minorities in the selection of speakers and organizing committee, starting with 2 of the 3 ICCC co-chairs being a woman or a minority. We will target at least ~40% of plenary speakers to be women and ~10% under-represented minorities. Childcare will be provided. The 11th ICCC is significant because focuses on an important infectious disease afflicting both immunocompromised and immunocompetent people. This is the only such conference that brings together basic scientists and clinical investigators who investigate cryptococcosis. This is the first time the conference will be held in Africa with objectives: 1) to build new US-African translational research collaborations; 2) to define the important clinical, translational, and basic science research agenda to forge new avenues for novel prevention and treatment strategies.

抽象的 该提案请求对第十一届隐球菌国际会议给予部分支持 隐球菌病 (ICCC) 将于 2022 年 1 月 10 日至 14 日在乌干达坎帕拉举行。隐球菌病占 全球 15% 的艾滋病相关死亡病例仍然是最常见的神经感染。 在撒哈拉以南非洲地区的所有成年人中，这种疾病仍然是对越来越多的非艾滋病毒感染者的主要威胁 免疫功能低下的人。 ICCC 的广泛而长期的目标是汇集该领域世界领先的研究人员 扩大领域，促进跨学科讨论、研究和临床合作，以增强我们的能力 了解隐球菌致病机制和隐球菌病的最佳管理。 这次会议的具体目标是召集领先的专家，他们的专业知识涵盖关键领域 该领域的各个领域，以及早期职业和初级研究人员、学生和博士后。 预计将接待 300 名参与者，该计划将分为 17 个会议，涵盖不同的领域。 病原体的特性和特征以及宿主的易感性和免疫力，强调 重要的是，会议将提供什么使正常宿主突然容易感染这种疾病。 广泛涵盖当前和新型抗真菌药物——从临床前开发计划到 正在进行/未来的临床试验摘要来自初级研究人员、研究生和博士后研究员。 会议将举办两场墙报会议。 这将允许所有参与者积极为这些主题做出贡献，在 17 个会话块中，有 12 个块。 将同时举行会议，以便较小的工作组能够开会，并允许更多的学生/受训者 R13 资源将用于支持毕业生参与旅行补助金。 来自美国和非洲的学生，特别是代表性不足的少数族裔学者，他们提交了摘要。 我们将在选择演讲者和组织活动时寻求对妇女和少数族裔的平等对待 委员会，从 3 位 ICCC 联合主席中的 2 位开始，我们将至少瞄准女性或少数族裔。 约 40% 的全体发言者为女性，约 10% 的代表性不足的少数族裔将获得儿童保育服务。 第 11 届 ICCC 意义重大，因为重点关注了一种影响两国人民的重要传染病 这是唯一将免疫功能低下和免疫功能正常的人聚集在一起的会议。 基础科学家和临床研究人员对隐球菌病进行研究，这是第一次。 会议将在非洲举行，目标是：1）建立新的美非转化研究 合作；2）确定重要的临床、转化和基础科学研究议程 新的预防和治疗策略的新途径。