University of Michigan BACPAC Mechanistic Research Center

密歇根大学BACPAC机理研究中心

• 批准号: 10395664
• 负责人: Daniel J Clauw
• 金额: $ 12.94万
• 依托单位: UNIVERSITY OF MICHIGAN AT ANN ARBOR
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-06-01 至 2024-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10395664
• 关键词: Address; Advisory Committees; American; Chronic; Chronic Fatigue Syndrome; Chronic low back pain; Classification; Common Data Element; Comprehension; Consult; Consumption; Diagnostic; Ensure; Etiology; Female; Fibromyalgia; Healthcare; Helping to End Addiction Long-term; Individual; Institute of Medicine (U.S.); Institution; Interstitial Cystitis; Irritable Bowel Syndrome; Knowledge; Logic; Measures; Methods; Michigan; Migraine; National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Institute of Dental and Craniofacial Research; National Institute of Diabetes and Digestive and Kidney Diseases; Neurobiology; Pain; Patients; Persons; Reporting; Research; Research Personnel; Sampling; Screening procedure; Standardization; Temporomandibular Joint Disorders; Tension Headache; United States National Institutes of Health; Universities; Validation; Vulvodynia; Woman; Women' s Health; central sensitization; chronic pain; chronic painful condition; cognitive interview; digital; endometriosis; instrument; male; neurobiological mechanism; pain relief; programs; targeted treatment; tool; usability; validation studies

Project Summary / Abstract Chronic Overlapping Pain Conditions (COPCs) represent up to 50% of all chronic pain cases, occur more commonly in women, and can be more debilitating than other forms of chronic pain. These conditions include but are not limited to the following: temporomandibular disorders (TMD), fibromyalgia (FM), irritable bowel syndrome (IBS), vulvodynia (VVD), interstitial cystitis/painful bladder syndrome (IC/PBS), painful endometriosis (ENDO), chronic tension type headache (cTTH), migraine headache (MI), chronic low back pain (cLBP), and myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). Common neurobiological substrates (e.g., central sensitization) have been suspected to account for the overlap; but until recently, it has been difficult to efficiently classify each of these conditions within individuals. A digital, logic driven classification tool has been developed for this purpose but access to the tool remains limited. Here we propose converting this COPC classification tool into the REDCap format so that it will be more broadly accessible by academic researchers including those involved in the HEAL initiative. Following the REDCap conversion of the COPC screener, a small validation study will help to assure that the new format retains its construct validity, usability, and equivalence to existing versions of the instrument.

项目概要/摘要 慢性重叠疼痛 (COPC) 占所有慢性疼痛病例的 50%，发生率更高 常见于女性，并且比其他形式的慢性疼痛更容易使人衰弱。这些条件包括 但不限于以下疾病：颞下颌关节紊乱病 (TMD)、纤维肌痛 (FM)、肠易激 综合征 (IBS)、外阴痛 (VVD)、间质性膀胱炎/膀胱疼痛综合征 (IC/PBS)、疼痛性子宫内膜异位症 (ENDO)、慢性紧张型头痛 (cTTH)、偏头痛 (MI)、慢性腰痛 (cLBP) 和 肌痛性脑脊髓炎/慢性疲劳综合征（ME/CFS）。常见的神经生物学底物（例如， 中枢敏化）被怀疑是造成重叠的原因；但直到最近，还很难 有效地对个体中的每一种情况进行分类。数字逻辑驱动的分类工具已经 为此目的而开发，但对该工具的访问仍然有限。这里我们建议转换这个COPC 分类工具转换为 REDCap 格式，以便学术研究人员更广泛地使用它 包括那些参与 HEAL 倡议的人。 COPC 筛选器经过 REDCap 转换后， 小型验证研究将有助于确保新格式保留其结构有效性、可用性和 与仪器现有版本的等效性。