Core C: Biostatistics and Bioinformatics Core

核心 C：生物统计学和生物信息学核心

基本信息

批准号：
10331961
负责人：
Riyue Bao
金额：
$ 21.15万
依托单位：
UNIVERSITY OF PITTSBURGH AT PITTSBURGH
依托单位国家：
美国
项目类别：
财政年份：
2004
资助国家：
美国
起止时间：
2004-07-01 至 2027-08-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10331961
关键词：
Aftercare Animals Applications Grants Bayesian learning Bioinformatics Biological Biometry Cancer Center Clinic Clinical Clinical Cancer Center Clinical Data Clinical Protocols Clinical Research Computer Analysis Data Data Analyses Development Ensure Experimental Designs Genomics Goals Head and Neck Cancer Head and Neck Squamous Cell Carcinoma Immunohistochemistry Immunologics In Vitro Individual Laboratories Malignant Neoplasms Manuscripts Methods Nature Patients Preparation Program Development Protocols documentation Quality Control Reporting Reproducibility Research Research Design Research Personnel Research Project Grants Resource Sharing Services Skin Cancer Specimen Techniques Translational Research Visualization Work anticancer research career development compare effectiveness data management data quality/integrity data sharing design experience experimental study in vivo innovation member multidimensional data stem translational study

项目摘要

PROJECT SUMMARY – BIOSTATISTICS/BIOINFORMATICS CORE (CORE C) The Biostatistics/Bioinformatics Core (Core C) of the Hillman Cancer Center (HCC) HN SPORE provides services for the design of experiments and the analysis of in vitro, in vivo, clinical, translational and -omics data. The investigators and staff of both segments of the Core have significant experience in research in head and neck cancers, so that data are analyzed in the appropriate scientific context, increasing the Core's efficiency and effectiveness compared to general purpose data analysis services. Biostatistics and Bioinformatics combines classic statistical techniques with contemporary Bayesian, machine learning and genomics methods to ensure that every research project, Developmental Research Program and Career Development Program awardee in the SPORE has access to the most appropriate analyses. The Core will also work closely with Core A (OSD) and Core B to ensure that data flows between laboratories, clinics and analysts are efficient and that data and resource sharing can be effective and comprehensive. This Core C Co-Directors are Dr. Daniel Normolle (Biostatistics) and Dr. Riyue Bao (Bioinformatics) who have assembled an excellent team to help achieve the goals of the HN SPORE.

项目摘要 – 生物统计学/生物信息学核心（核心 C） Hillman 癌症中心 (HCC) HN SPORE 的生物统计学/生物信息学核心（核心 C）提供实验设计和体外、体内、临床、转化和组学分析服务核心两个部门的研究人员和工作人员在头部研究方面拥有丰富的经验。和颈部癌症，以便在适当的科学背景下分析数据，增加核心的与通用数据分析服务相比的效率和有效性。生物信息学将经典统计技术与当代贝叶斯、机器学习和基因组学方法确保每个研究项目、发展研究计划和职业 SPORE 开发计划获奖者可以获得最合适的分析。还与核心 A (OSD) 和核心 B 密切合作，确保实验室、诊所和诊所之间的数据流动分析师效率高，数据和资源共享有效且全面。该核心 C 联合主任是 Daniel Normolle 博士（生物统计学）和 Riyue Bao 博士（生物信息学），他们组建了一支优秀的团队来帮助实现 HN SPORE 的目标。