Lab Animal Shared Resource

实验动物共享资源

• 批准号: 9070344
• 负责人: DONALD L TRUMP
• 金额: $ 18.49万
• 依托单位: ROSWELL PARK CANCER INSTITUTE CORP
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/9070344
• 关键词: Absence of pain sensation; Accreditation; Animal Experimentation; Animal Husbandry; Animals; Basic Science; Budgets; Cancer Center; Cancer Center Support Grant; Cancer Research Project; Canis familiaris; Caring; Clinical; Clinical Trials; Complex; Development; Diagnostic Services; Ensure; Faculty; Family suidae; Funding; Growth; Health; Human; Image; Institutes; Institution; Instruction; International; Laboratory Animal Shared Resource; Laboratory Animals; Laboratory Personnel; Medical; Medical Research; Monitor; Mus; Operative Surgical Procedures; Oryctolagus cuniculus; Peer Review; Postoperative Care; Preventive; Qualifying; Rattus; Recruitment Activity; Regulation; Reporting; Research; Research Personnel; Resource Sharing; Resources; Roswell Park Cancer Institute; Scientist; Services; Site; Techniques; Training and Education; Translational Research; Veterinarians; Woodchuck; animal care; anticancer research; cancer cell; clinical care; cost effective; investigator training; meetings; member; programs; research clinical testing; square foot; surgical service

The Laboratory Animal Shared Resource (LAR) provides the entire spectrum of animal-related research services, including specialized veterinary medical care, expert animal husbandry, diagnostic and surgical services, imaging resources and training of investigators and laboratory personnel. The LAR promotes the humane care and use of laboratory animals in support of basic and translational research. Although the majority of animal care services provided by LAR are related to mice and rats, the animal program at RPCI has been expanded to include larger species including rabbits, woodchucks, dogs and pigs. Two buildings are designated for the LAR. The main site is the four-story 45,000 net square foot (nsf) Vivarium, which opened in 1998, located in the Medical Research Complex. An additional 5,000 nsf is utilized in the adjacent Cancer Cell Center. The LAR Facility Director and Attending Veterinarian, Sandra (Buitrago) Sexton DVM, oversees the Veterinary Program to a standard that ensures that all services meet or exceed the criteria set in the LAR's AAALAC accreditation. She is assisted by a qualified support staff for administration and management of the facility and for provision of specialized veterinary medical care. Dr. Sexton provides training and education programs for researchers on proper care and use of animals, including: • Clinical care of laboratory animals (proper handling, postoperative care, analgesia and surgery techniques) • A preventive animal health-monitoring program • Coordination of import/export of animals to and from other facilities, promoting a strong collaborative relationship with scientists and clinicians at other institutions with major focus in cancer research. A total of 46 staff members comprise the LAR workforce, with CCSG direct effort of 5.86 FTE. Continued support through the NCI permits the Resource to provide a standard of animal care that exceeds applicable state and federal regulations, maintains full AAALAC International accreditation, and furnishes investigators with a comprehensive program for safe, appropriate and cost-effective research animal use. Prioritization for Resource utilization is 1) peer-review-funded CCSG members; 2) non-peer-review-funded CCSG members; 3) non-members and academic collaborators; and 4) external users. During the reporting period, the Laboratory Animal Shared Resource has served 83 members from 6 research programs, with 72% utilization by CCSG members with peer reviewed funding. The CCSG support provides 4% of the overall proposed budget.

实验室动物共享资源（LAR）提供了整个与动物有关的研究 服务，包括专业的兽医医疗服务，专家畜牧业，诊断和外科手术 服务，成像资源和研究人员和实验室人员的培训。 LAR推广 人类护理和实验动物的使用，以支持基础和翻译研究。虽然 LAR提供的大多数动物护理服务与RPCI的动物计划有关的小鼠和大鼠有关 已经扩展到包括兔子，木屑，狗和猪在内的较大物种。两座建筑物 被指定为LAR。主要地点是四层楼的45,000净平方英尺（NSF）Vivarium，它 于1998年开放，位于医学研究综合体。在相邻的 癌细胞中心。 LAR设施主管兼兽医Sandra（Buitrago）Sexton DVM负责监督 兽医计划符合一个标准，以确保所有服务都达到或超过LAR的标准 AAALAC认证。她得到了合格的支持人员的协助，用于管理和管理 设施和提供专门的兽医医疗服务。 Sexton博士提供培训和教育 针对适当护理和使用动物的研究人员的计划，包括： •实验动物的临床护理（适当处理，术后护理，镇痛和手术 技术） •预防性动物健康监测计划 •将动物进出的动物与其他设施进行协调，促进强大的合作 与其他机构的科学家和临床医生的关系，重点是癌症研究。 共有46名员工组成了LAR劳动力，CCSG直接努力为5.86 fte。持续 通过NCI的支持允许资源提供超过适用的动物护理标准 州和联邦法规，维持AAAALAC国际认证并提供调查人员 通过一项综合计划，以进行安全，适当和具有成本效益的研究动物使用。优先级 资源利用率为1）同行评估资助的CCSG成员； 2）非Per-Review资助的CCSG成员； 3）非成员和学术合作者； 4）外部用户。在报告期间， 实验室动物共享资源为来自6个研究计划的83名成员提供了服务，利用72％ 由CCSG成员拥有同行审查的资金。 CCSG支持提供了4％的总体建议 预算。