Administrative Core

行政核心

基本信息

批准号：
10276390
负责人：
THOMAS T PERLS
金额：
$ 20.08万
依托单位：
BOSTON UNIVERSITY MEDICAL CAMPUS
依托单位国家：
美国
项目类别：
财政年份：
2021
资助国家：
美国
起止时间：
2021-09-30 至 2026-08-31
项目状态：
未结题

项目摘要

The Administrative Core provides the overall leadership for this U19 study, Resistance/Resilience to Alzheimer's Disease in Centenarians and their Offspring (RADCO) and it acts as the communication hub for the 3 cores and 2 projects, NIA scientific officers, the Lead PI for the Single IRB and the OSMB (the RADCO community). The core supports and encourages optimal interactions amongst the RADCO community in part by facilitating all of the study-wide, core- and project-specific video conference calls and posting the minutes and action items on the Study's internal Confluence-based website. The Core provides the leadership of the Publications and Presentations and Ancillary Studies Committees and orchestrates triannual RADCO-wide video conference meetings to discuss progress in achieving the aims, to update everyone on what others are doing and provides, particularly for junior investigators, opportunities to present their work. In years 2 and 4, the Spring meeting is held in person in Bethesda. The Administrative Core also coordinates with NIA staff, biannual meetings with the OSMB. The Core leads the outreach to the greater scientific community with the creation and maintenance of the RADCO's public facing website and orchestration of publicly available and well-advertised biannual scientific workshops. These scientific outreach efforts also include implementation of NIA's Alzheimer's Disease-related data sharing policy by working with the Phenotyping and Biospecimen and the Neuroimaging Cores to perform quality control, curation and transfer of all generated data to the AD Knowledge Portal within 3 months of the data becoming available for analyses. All of these responsibilities are integral to successfully achieving the goals of the proposed research and they are reiterated as the following specific aims.

行政核心为这项 U19 研究提供全面领导，百岁老人及其后代对阿尔茨海默病的抵抗力/恢复力 (RADCO)，它作为 3 个核心和 2 个项目的通信枢纽，NIA 科学官员、单一 IRB 和 OSMB（RADCO 社区）的首席 PI。核心支持并鼓励 RADCO 社区之间的最佳互动，部分原因是促进所有研究范围、核心和特定项目的视频电话会议，并发布该研究基于 Confluence 的内部网站上的会议记录和行动项目。核心提供出版物、演示文稿和辅助研究委员会的领导以及每年召开三次 RADCO 范围内的视频会议，讨论实现目标的进展情况目标是让每个人了解其他人正在做什么和提供什么，特别是对于初级学生调查员，展示他们工作的机会。在第 2 年和第 4 年，春季会议在贝塞斯达的人。行政核心还与 NIA 工作人员进行协调，每年举行两次会议与 OSMB 合作。核心通过创造引领了更大的科学界的拓展维护 RADCO 面向公众的网站并协调公开可用的内容以及广为宣传的一年两次的科学研讨会。这些科学推广工作还包括通过与 NIA 合作实施阿尔茨海默氏病相关数据共享政策表型分析和生物样本以及神经影像核心进行质量控制、管理并在数据产生后 3 个月内将所有生成的数据传输到 AD 知识门户可用于分析。所有这些责任对于成功实现目标都是不可或缺的拟议研究的目标，并重申为以下具体目标。