Near-Peer Mentoring in Environmental Health: Chemical Exposures and Disease Risk

环境健康中的近同伴指导：化学品接触和疾病风险

• 批准号: 10543071
• 负责人: Laura N. Vandenberg
• 金额: $ 10.63万
• 依托单位: UNIVERSITY OF MASSACHUSETTS AMHERST
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-01-01 至 2025-12-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10543071
• 关键词: Address; Adverse effects; Animals; Area; Autoimmune Diseases; Biomedical Research; Cardiovascular Diseases; Cell model; Cellular biology; Chemical Engineering; Chemical Exposure; Chemicals; Chemistry; Collaborations; Communication; Communication Tools; Communities; Complement; Complex; Development; Disabled Persons; Discipline; Disease; Disease Outcome; Disease model; Endocrinology; Engineering; Environmental Engineering technology; Environmental Health; Epidemiologist; Epidemiology; Exposure to; Faculty; Fostering; Generations; Goals; Health; High School Student; Human; Individual; Interdisciplinary Study; Investments; Laboratories; Learning; Lesbian Gay Bisexual Transgender Queer; Malignant Neoplasms; Mentors; Metabolic Diseases; Methods; Mission; Molecular; Molecular Biology; National Institute of Environmental Health Sciences; Non-Insulin-Dependent Diabetes Mellitus; Parabens; Participant; Persons; Pollution; Population; Problem Solving; Public Health; Reproducibility; Research; Research Project Grants; Risk; STEM field; Safety; School-Age Population; Science; Scientist; Societies; Students; Toxicology; Training; Training Programs; Triclosan; Underrepresented Minority; Underrepresented Populations; Veterans; Woman; Work; Writing; animation; career; disorder risk; economic disparity; eleventh grade; environmental chemical; environmental chemical exposure; ethnic minority; experience; faculty mentor; girls; hands on research; hazard; high school; human disease; imidacloprid; improved; interest; learning community; molecular modeling; ninth grade; peer coaching; phthalates; podcast; programs; racial minority; recruit; remediation; responsible research conduct; science education; skills; social media; summer program; summer research; tenth grade; tool; undergraduate student; underserved community; young woman

Project Summary The overarching goal of this R25 application is to provide training to diverse high school and undergraduate students who will work with supportive faculty mentors to understand how environmental chemical exposures contribute to non-communicable diseases, and how hazard and/or exposure mitigation can improve health. Program faculty come from a diverse range of disciplines: toxicology, endocrinology, cell and molecular biology, veterinary and animal sciences, chemistry, epidemiology, chemical engineering, civil and environmental engineering, and science communication. We will focus on recruiting women and individuals from underrepresented groups to participate in this summer program, which includes three aims: 1) To involve high school age young women in introductory summer research experiences and recruit those with an interest in participating in research projects or science communication projects. By partnering with the local Girls Inc. organization, we will offer week-long introductory training programs for 9th grade girls from diverse but underserved communities in Western MA. With 24-26 girls participating every year, we will use this program to recruit 10th and 11th grade girls to participate in Aims 2 and 3. 2) To create a learning community focused on understanding how environmental chemical exposures contribute to non-communicable diseases and develop scientific strategies to create solutions to these challenging problems. High school and undergraduate students will work with UMass faculty to understand how environmental chemical exposures contribute to non-communicable diseases, and how hazards and/or exposures can be mitigated. Research will focus on one of these areas: • molecular and cellular models of diseases relevant to environmental chemical exposures; • characterizing chemical exposures and their association with human diseases; • understanding the effects of environmental chemicals on conditions such as cancer and metabolic diseases; • creating solutions for exposures to hazardous environmental chemicals including use of green chemistry principles to avoid hazards entirely and pollution remediation when exposures cannot be avoided. 3) To train diverse participants in methods to communicate complex environmental health concepts in the context of our learning community and in broader communities. High school and undergraduate students will work to create science communication tools, aimed at educating a lay audience about one or more topic addressed in the laboratories in Aim 2. Communication tools could include static or animated infographics, informational videos, podcasts, or other social media tools.

项目摘要 该R25应用程序的总体目标是为潜水员高中和本科提供培训 将与支持教师的导师合作以了解环境化学的学生 暴露会导致非传染性疾病，以及减轻危害和/或暴露的情况如何 改善健康。计划教师来自潜水员的学科：毒理学，内分泌学，细胞和 分子生物学，兽医和动物科学，化学，流行病学，化学工程，民用和 环境工程和科学传播。我们将专注于招募妇女和个人 从代表性不足的小组参加本夏季计划，其中包括三个目标： 1）让高中时代的年轻女性参与夏季研究经验并招募这些经验 有兴趣参加研究项目或科学通信项目。通过与 当地女孩公司组织，我们将为长达一周的介绍培训计划，为9年级女孩的培训计划 潜水员但在马萨诸塞州西部服务不足的社区。每年有24-26名女孩参加，我们将使用此 招募10年级和11年级女孩参加目标2和3的计划。 2）创建一个专注于了解环境化学暴露的学习社区 为非通信疾病做出贡献，并制定科学策略来为这些疾病创建解决方案 Challenging problems.高中和本科生将与UMass教师合作了解 环境化学暴露如何导致非通信疾病，以及危害和/或危害和/或 可以减轻暴露。研究将重点关注其中一个领域： •与环境化学暴露有关的疾病的分子和细胞模型； •表征化学暴露及其与人类疾病的关联； •了解环境化学物质对癌症和代谢等疾病的影响 疾病； •为暴露于危险环境化学物质（包括使用绿色化学）的曝光解决方案 当无法避免暴露时，完全避免危害的原则和污染修复。 3）培训潜水员参与者的方法，以传达复杂的环境健康概念 我们学习社区和更广泛社区的背景。高中和本科生将 努力创建科学沟通工具，旨在教育一个或多个主题 在AIM 2中的实验室中解决。通信工具可以包括静态或动画信息图表， 信息视频，播客或其他社交媒体工具。

项目成果

Quantifying the relationship between SARS-CoV-2 wastewater concentrations and building-level COVID-19 prevalence at an isolation residence using a passive sampling approach.

使用被动采样方法量化隔离住宅中 SARS-CoV-2 废水浓度与建筑层面的 COVID-19 流行率之间的关系。

• DOI: 10.1101/2022.04.07.22273534
• 发表时间: 2022
• 期刊: medRxiv : the preprint server for health sciences
• 作者: Acer,PatrickT;Kelly,LaurenM;Lover,AndrewA;Butler,CaitlynS
• 通讯作者: Butler,CaitlynS

Quantifying the Relationship between SARS-CoV-2 Wastewater Concentrations and Building-Level COVID-19 Prevalence at an Isolation Residence: A Passive Sampling Approach.

• DOI: 10.3390/ijerph191811245
• 发表时间: 2022-09-07
• 期刊: INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
• 作者: Acer, Patrick T.;Kelly, Lauren M.;Lover, Andrew A.;Butler, Caitlyn S.
• 通讯作者: Butler, Caitlyn S.