An Integrated Life-course Approach for Person-centred Solutions and Care for Ageing with Multi-morbidity in the European Regions - STAGE; Stay Healthy Through Ageing

欧洲地区以人为本的解决方案和针对多种疾病的老龄化护理的综合生命全程方法 - STAGE；

• 批准号: 10112787
• 金额: $ 70.34万
• 依托单位: BETA TECHNOLOGY LIMITED
• 依托单位国家: 英国
• 项目类别: EU-Funded
• 财政年份: 2024
• 资助国家: 英国
• 起止时间: 2024 至 无数据
• 项目状态: 未结题
• 来源: https://gtr.ukri.org/projects?ref=10112787
• 关键词: Integrated; Life; course; Approach; Person

STAGE aims to demonstrate the importance and feasibility of a life-course approach to prevent accelerated ageing, as defined by the accumulation of multi-morbidity, and to integrate knowledge into transferable person-centred solutions for early diagnosis and screening, treatment and long-term management of multi-morbidity. To achieve this, STAGE is proposing a life-course approach to better understand ageing with multi-morbidity, providing evidence-based solutions to support the transformation of healthcare to address the profound health and demographic challenges ahead. The approach capitalises on European collaborations of longitudinal cohorts and biobanks spanning the entire life-course, actioning exposome and disease networks trajectory analysis, as well as, the biology of ageing, to explore how a person develops ageing with multi-morbidity. The project objectives integrate an ethical, social, historical, and infrastructural framework; environmental, epidemiological and biological life-course approaches; artificial intelligence powered integrated person centred solutions and applications; cohort-based clinical studies; and a FAIR (findable, accessible, interoperable and reusable) life-course health and geospatial data portal with robust management, dissemination, engagement and exploitation activities. STAGE's evidence based methods will translate into a person-centred prevention and care intervention in longitudinal cohorts in Finland and Germany, co designed with citizens, patients, healthcare providers, SMEs, and policymakers. It will also embed social sciences and humanities and engage stakeholders to develop a neighbourhood healthy ageing index, person-centred predictions of multi-morbidity, and healthcare and policy recommendations. Ultimately, STAGE will create solutions for agile, high-quality, person-centred health and care services that are life-course and gender sensitive, needs-based, and designed to enhance resilience and participation.

阶段的目的是证明生命过程方法的重要性和可行性，以防止加速衰老，这是由多种多样的积累所定义的，并将知识整合到可转移的人以人为中心的解决方案中，以早期诊断和筛查，治疗和长期管理多种多样化。为了实现这一目标，阶段正在提出一种生活方式的方法，以通过多种多元车更好地了解衰老，从而提供基于证据的解决方案来支持医疗保健的转型，以应对未来的深刻健康和人口统计挑战。该方法利用了纵向人群和生物库的欧洲合作，这些合作涵盖了整个生命时期，动作的外汇和疾病网络轨迹分析，以及衰老的生物学，以探索一个人如何通过多种多物种发展衰老。项目目标融合了道德，社会，历史和基础设施框架；环境，流行病学和生物学生命过程的方法；人工智能为以综合人为中心的解决方案和应用；基于队列的临床研究；以及一个公平的（可访问，可互操作和可重复使用的）生活方式健康和地理空间数据门户，并具有强大的管理，传播，参与和剥削活动。阶段的基于证据的方法将转化为芬兰和德国纵向人群中以人为本的预防和护理干预，由公民，患者，医疗保健提供者，中小型企业和政策制定者设计。它还将嵌入社会科学和人文科学，并吸引利益相关者开发一个邻里健康的老龄化指数，以人为本的多种多人预测以及医疗保健和政策建议。最终，阶段将为敏捷，高质量，以人身份的健康和护理服务创建解决方案，这些解决方案是生活方式和性别敏感，基于需求的，并旨在增强韧性和参与的旨在。