Enhanced Imaging for Visual Prostheses

视觉假肢的增强成像

基本信息

批准号：
10483085
负责人：
Gregory John Seifert
金额：
$ 73.11万
依托单位：
ADVANCED MEDICAL ELECTRONICS CORPORATION
依托单位国家：
美国
项目类别：
财政年份：
2014
资助国家：
美国
起止时间：
2014-05-01 至 2024-08-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10483085
关键词：
Businesses Clinical Trials Collaborations Color Communities Computer software Data Development Diabetic Retinopathy Disease Doctor of Philosophy Documentation Electric Stimulation Environment Evaluation Eye Eye Injuries Financial compensation Funding Glaucoma Grant Head Home Image Image Enhancement Imagery Individual Institutes Instruction Lead Light Macular degeneration Medical Medical Electronics Modality Ocular Prosthesis Ophthalmology Panthera leo Participant Penetration Persons Phase Pilot Projects Principal Investigator Process Production Prosthesis Readiness Rehabilitation Centers Rehabilitation therapy Research Resolution Retina Retinitis Pigmentosa Self-Help Devices Silicon Small Business Innovation Research Grant Software Validation System Techniques Technology Temperature Test Result Testing Time Training Training Programs Translating Trauma Universities Visible Radiation Vision Vision research Visual Visual Cortex Visual Perception Visual impairment Visually Impaired Persons Work base blind cohort commercialization design experience imager imaging modality imaging system improved intelligent algorithm medical schools multidisciplinary optic nerve disorder programs prosthesis wearer prototype retina implantation retinal prosthesis sensor verification and validation vision aid vision rehabilitation

Businesses Clinical Trials Collaborations Color Communities Computer software Data Development Diabetic Retinopathy Disease Doctor of Philosophy Documentation Electric Stimulation Environment Evaluation Eye Eye Injuries Financial compensation Funding Glaucoma Grant Head Home Image Image Enhancement Imagery Individual Institutes Instruction Lead Light Macular degeneration Medical Medical Electronics Modality Ocular Prosthesis Ophthalmology Panthera leo Participant Penetration Persons Phase Pilot Projects Principal Investigator Process Production Prosthesis Readiness Rehabilitation Centers Rehabilitation therapy Research Resolution Retina Retinitis Pigmentosa Self-Help Devices Silicon Small Business Innovation Research Grant Software Validation System Techniques Technology Temperature Test Result Testing Time Training Training Programs Translating Trauma Universities Visible Radiation Vision Vision research Visual Visual Cortex Visual Perception Visual impairment Visually Impaired Persons Work base blind cohort commercialization design experience imager imaging modality imaging system improved intelligent algorithm medical schools multidisciplinary optic nerve disorder programs prosthesis wearer prototype retina implantation retinal prosthesis sensor verification and validation vision aid vision rehabilitation

展开

项目摘要

Project Summary/Abstract The proposed project relates to the commercialization of a promising new thermal/visual imaging system to be used as an input modality to visual prostheses and other low vision aids. Visual prostheses, including Second Sight's Argus® II retinal prosthesis, which restores partial vision to people blinded by diseases such as retinitis pigmentosa and macular degeneration, and Second Sight's Orion® visual cortical prosthesis, which restores partial vision to people blinded by diseases such as retinitis pigmentosa, macular degeneration, glaucoma, diabetic retinopathy, eye injury/trauma, optic nerve disease etc., use cameras or other sensors to provide electrical stimulation directly to the retina or visual cortex of the user to elicit visual perception. Unfortunately, ordinary light and color information is difficult for wearers to effectively process in many important tasks with the limited perceived spatial resolution of the prostheses and other low vision aids. Current compensation techniques in reduced resolution systems apply enhancement, magnification, and panning of visible light imagery, and these techniques have utility. However, as we have convincingly demonstrated in phases I and II of the SBIR-supported development project, other types of imaging more naturally align with the limited resolution of visual prostheses in important tasks such as people finding and mobility. In this proposed CRP project, we will advance the phase II developed production-prototype system into commercial production and complete all required verification and validation testing to achieve FDA approval. Completed production systems will be distributed to prosthesis recipients who will undergo training in their use and then be allowed to evaluate the system in their home and community environment. Through these evaluations the end utility of the system in real-world use will be evaluated.

项目摘要/摘要提出的项目与承诺新的热/视觉成像系统的商业化有关用作视觉假体和其他低视力辅助工具的输入方式。视觉假肢，包括第二 Sight'sArgus®II视网膜假体，该假体恢复了因视网膜炎等疾病而蒙蔽的人的部分视力色素色和黄斑变性，以及第二镜的Orion®视觉皮质假体，恢复对被视网膜炎色素炎，黄斑变性，青光眼，青光眼，诸如视网膜炎蒙蔽的人的部分视力糖尿病性视网膜病，眼部损伤/创伤，视神经疾病等，使用相机或其他传感器提供直接向用户的视网膜或视觉皮层进行电刺激，以引起视觉感知。很遗憾，对于佩戴者而言，普通的光线和颜色信息很难在许多重要任务中有效地处理有限的假体和其他低视力辅助工具的空间分辨率有限。当前补偿减少分辨率系统中的技术应用可见光的增强，放大和平移图像和这些技术具有实用性。但是，正如我们在第I和II阶段令人信服地证明的那样在SBIR支持的开发项目中，其他类型的成像更自然地与有限在人们发现和流动性等重要任务中解决视觉假体。在这个建议的CRP中项目，我们将把第二阶段开发的生产 - 原型系统推向商业生产和完成所有必需的验证和验证测试，以获得FDA批准。完成的生产系统将分配给假肢收件人，他们将在使用中接受培训，然后被允许评估其家庭和社区环境中的系统。通过这些评估，将评估现实世界中的系统。