Regulatory Science in Environmental Health and Toxicology

环境健康和毒理学监管科学

• 批准号: 10410082
• 负责人: Ivan Rusyn
• 金额: $ 49.24万
• 依托单位: TEXAS A&M UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-07-01 至 2027-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10410082
• 关键词: Environmental Health; Science; environmental toxicology

PROJECT DESCRIPTION Regulatory Science in Environmental Health and Toxicology This proposal is to continue the T32 program in “Regulatory Science in Environmental Health and Toxicology” at Texas A&M University. Funds are requested to support eight pre-doctoral (Ph.D. candidates) and two post- doctoral trainees in the existing highly integrated degree-granting Interdisciplinary Faculty of Toxicology program. Our goal remains to prepare trainees to function as independent researchers and/or practitioners in a multidisciplinary setting, by providing training in mechanistic research and risk assessment with a focus on scientifically sound, risk-based regulatory evaluations of the effects of drugs and other chemicals on human health and the environment. To achieve this goal, didactic and research experiences are offered by a team of 20 outstanding investigators who specialize in mechanistic toxicology, community engagement, exposure assessment/environmental chemistry, public policy, epidemiology, biomedical engineering, and data science and modeling. Recruitment is conducted through traditional external advertisement and professional societies, as well as from a number of existing Texas A&M programs that offer research experience for undergraduates, and public health and toxicology masters-level traineeship. Pre-doctoral trainees undertake two laboratory rotations in their first year in the program and follow a structured core academic curriculum that includes basic and advanced toxicology, histopathology, pharmacology, biostatistics and research ethics, combined with courses in risk assessment and exposure assessment. In the second year, additional specialized training is offered through elective courses that further prepare trainees for careers in research and/or public health practice. Distinctive features of the program are (i) a strongly encouraged hands-on summer externship through a broad and diverse network of state and federal governmental regulatory agencies, companis and non- governmental organizations; and (ii) a series of special programs in the form of boot camps and special workshops on a wide range of trainee-selected topics (scientific writing, presentation, interview skills, disaster research and data science). Following the first two years, trainee support for both pre- and post-doctoral fellows shifts to their mentor’s or independent funding. All mentors have strong records of competitive support from Federal, State and other sources and this group of mentors is exceptionally well balanced with respect to relevant scientific expertise, sex and academic career level. Graduates from the program are highly successful in academia, and sought-after by employers in the industry, governmental agencies and other professional settings. Our trainees improve public health protection through innovative and rigorous mechanistic research and risk assessment practice in support of rigorous scientific evidence-based regulatory decision-making.

项目描述 环境健康和毒理学的监管科学 该建议是继续在“环境健康和毒理学方面的监管科学”领域继续进行T32计划。 在德克萨斯农工大学。要求资金支持八个博士前（博士学位）和两名后 现有的高度综合学位授予毒理学学院的博士学员 程序。我们的目标仍然是使受训者成为独立研究人员和/或从业人员的目标 多学科环境，通过提供机械研究和风险评估的培训，重点 对药物和其他化学物质对人的影响的科学声音，基于风险的调节评估 健康与环境。为了实现这一目标，由一组团队提供了教学经验和研究经验 20名专门从事机械毒理学，社区参与，暴露的杰出调查员 评估/环境化学，公共政策，流行病学，生物医学工程和数据科学 和建模。招聘是通过传统的外部广告和专业社会进行的 以及许多现有的得克萨斯州A＆M计划，这些计划为大学生提供研究经验， 以及公共卫生和毒理学硕士级的实习生。博士前的实习生从事两个实验室 在该计划的第一年轮换，并遵循包括基本的结构化核心学术课程 以及先进的毒理学，组织病理学，药理学，生物统计学和研究伦理，并结合 风险评估和暴露评估的课程。在第二年，其他专业培训是 通过选修课程提供，进一步为学员准备研究和/或公共卫生的职业 实践。该计划的独特特征是（i）通过 州和联邦政府监管机构，公司和非 - 一个广泛而多样的网络 政府组织； （ii）一系列以新兵训练营和特殊形式的特殊计划 有关各种学员阐述的主题（科学写作，演讲，面试技巧，灾难）的讲习班 研究与数据科学）。在头两年之后，受训者支持前和博士后研究员 转移到他们的导师或独立资金上。所有导师都有大量的竞争支持记录 联邦，州和其他来源以及这组导师在相关方面非常平衡 科学专业知识，性别和学术职业水平。该计划的毕业生在 在行业，政府机构和其他专业环境的雇主寻求学术界。 我们的学员通过创新和严格的机械研究和风险来改善公共卫生保护 评估实践，以支持严格的科学循证监管决策。