Center for Pediatric Brain Health

儿科脑健康中心

• 批准号: 10346722
• 负责人: Tony W Wilson
• 金额: $ 273.06万
• 依托单位: FATHER FLANAGAN'S BOYS' HOME
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-03-01 至 2027-01-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10346722
• 关键词: Advisory Committees; Americas; Area; Brain; Centers of Research Excellence; Child; Child Care; Childhood; Cognitive; Collaborations; Collection; Communities; Community Health; Community Outreach; Computers and Advanced Instrumentation; Core Facility; Development; Educational workshop; Ensure; Equipment; Evaluation; Event; Extramural Activities; Faculty; Family; Fostering; Funding; Future Generations; Future Teacher; Goals; Growth; Health; Home; Hospitals; Human; Image; Imaging technology; Infrastructure; Institutes; Institution; Internships; Lead; Magnetic Resonance Imaging; Magnetoencephalography; Mentors; Methods; Mission; Monitor; National Institute of General Medical Sciences; Nebraska; Neurosciences; Neurosciences Research; Outreach Research; Participant; Pilot Projects; Population; Publications; Publishing; Registries; Research; Research Infrastructure; Research Personnel; Research Project Grants; Research Support; Resources; Scientist; Senior Scientist; Series; Site; Structure; System; Training; Training Programs; Voice; Work; base; boys; brain health; career; career development; cohesion; cohort; collaborative environment; experience; graduate student; improved; innovation; instrumentation; multidisciplinary; multimodal neuroimaging; neuroimaging; neuroregulation; next generation; novel; prisma; programs; relating to nervous system; research and development; square foot; training opportunity; welfare

Abstract/Summary: Overall Component This application for a Center of Biomedical Research Excellence (COBRE) would initiate a Center for Pediatric Brain Health to manage, support, and expand developmental neuroimaging and pediatric neuroscience research at Boys Town National Research Hospital (BTNRH) in Omaha, Nebraska. It is an opportune moment for pediatric neuroscience at BTNRH, as an organization-wide initiative to expand in this area has resulted in numerous faculty hires and the construction of a new state-of-the-art 15,000+ square feet Institute for Human Neuroscience. The proposed Center for Pediatric Brain Health will organize and support these new resources under a central umbrella, and provide critical programs to help grow the community and build cohesiveness around a common theme of pediatric neuroscience and brain health. The key components of the Center include an Administrative Core, one research core (i.e., the Neural Quantification & Imaging Core), four research project leaders (RPLs), a Supervisory & Mentoring Committee, and a cohort of established pediatric neuroscientists. Upon initiation of the Center, the Administrative Core will implement a comprehensive research support structure that includes mentoring and career developing resources, a pilot projects program, extensive training opportunities, two distinct seminar series, community outreach, and broad support of key research infrastructure (e.g., participant registry, shared research spaces). Training opportunities will include technical workshops, as well as internships and a postdoctoral neuroimaging training program for fostering the next generation of graduate students and Center faculty. In parallel, the Administrative Core will promote the launch of four RPLs and implement a career development and evaluation system, which will include a Supervisory & Mentoring Committee comprised of 10 senior scientists who will monitor progress and ensure each RPL and their two co-mentors reach critical milestones. Finally, the new Neural Quantification & Imaging Core will support and provide direct access to state- of-the-art instrumentation for pediatric neuroimaging, including a new 3-Tesla Siemens Prisma magnet, two Neo magnetoencephalographic (MEG) imaging units, a mock MRI scanner, and other major equipment, and will provide comprehensive analytical support for the most advanced neuroimaging analyses currently available. Notably, the Core will be the only site in the world to host two MEG Neo systems for quantifying human brain dynamics. The new Center will also support a cohort of senior scientists with expertise spanning multiple pediatric populations and different imaging technologies. Finally, the Center will receive exceptional institutional support, including funds for pilot projects, Core staffing, internships, major equipment expenses, and other initiatives, and will be directed by Dr. Tony Wilson who is a developmental cognitive neuroscientist with extensive experience in multimodal neuroimaging and an exceptional track record of extramural support, publications, and mentoring. Taken together, the expansive resources, support, and expertise within the new Center for Pediatric Brain Health will ensure that it has a major long-term impact on pediatric neuroscience research at BTNRH and beyond.

摘要/摘要：整体组件 该申请卓越生物医学研究中心（COBRE）将启动小儿中心 大脑健康以管理，支持和扩展发育神经影像学和小儿神经科学研究 在内布拉斯加州奥马哈的男孩镇国家研究医院（BTNRH）。这是儿科的合适时刻 BTNRH的神经科学作为一项在该领域扩展的组织倡议，导致了许多 教师雇用并建造了新的15,000平方英尺人类神经科学研究所。 拟议的小儿大脑健康中心将在中央组织和支持这些新资源 伞，并提供关键的计划，以帮助发展社区并围绕一个共同的凝聚力建立凝聚力 小儿神经科学和大脑健康的主题。该中心的关键组成部分包括管理 核心，一个研究核心（即神经定量和成像核心），四个研究项目负责人（RPLS）， 一个监督和指导委员会，以及一群既定的儿科神经科学家。启动 中心，行政核心将实施全面的研究支持结构，包括 指导和职业发展资源，试点项目计划，广泛的培训机会，两个 独特的研讨会系列，社区宣传以及对主要研究基础设施的广泛支持（例如，参与者 注册表，共享研究空间）。培训机会将包括技术研讨会以及实习 以及一项博士后神经影像学培训计划，用于培养下一代研究生和 中心教师。同时，行政核心将促进四个RPL的发布并实施职业 开发和评估系统将包括一个由10个组成的监督和指导委员会 高级科学家将监视进度并确保每个RPL及其两个副委员会达到关键 里程碑。最后，新的神经量化和成像核心将支持并直接访问状态 - 小儿神经影像学的艺术仪器，包括新的3-Tesla Siemens Prisma磁铁，两个NEO 磁脑电图（MEG）成像单元，模拟MRI扫描仪和其他主要设备，并将 为当前可用的最先进的神经影像学分析提供全面的分析支持。 值得注意的是，核心将是世界上唯一一个托管两个MEG NEO系统来量化人脑的网站 动力学。新中心还将支持一群具有多个小儿专业知识的高级科学家 种群和不同的成像技术。最后，该中心将获得卓越的机构支持， 包括用于试点项目的资金，核心人员配备，实习，主要设备费用和其他计划，以及 将由托尼·威尔逊（Tony Wilson）博士指导，他是一位具有丰富经验的发展认知神经科学家 在多模式的神经影像学以及壁外支持，出版物和指导的出色记录中。 综上 将确保它对BTNRH及其他地区的小儿神经科学研究产生重大长期影响。