Harnessing the power of technology to develop a population-based HIV prevention program for trans girls

利用技术的力量为跨性别女孩制定基于人口的艾滋病毒预防计划

• 批准号: 10308350
• 负责人: Michele L. Ybarra
• 金额: $ 50.41万
• 依托单位: CENTER FOR INNOVATIVE PUBLIC HEALTH RESEARCH
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-09-08 至 2025-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10308350
• 关键词: 18 year old; AIDS prevention; Address; Adolescence; Adolescent; Adoption; Advisory Committees; Affect; Area; Behavior; Behavioral; Centers for Disease Control and Prevention (U.S.); Clinical; Data; Decision Making; Ensure; Feedback; Focus Groups; Fostering; Gender; Gender Identity; Gender Role; Goals; HIV; HIV Seropositivity; HIV risk; HIV/STD; Health Status; Individual; Intervention; Intervention Studies; Mental Health; Minority Groups; Motivation; National Institute of Mental Health; Outcome; Outcome Measure; Population; Prevention program; Preventive; Property; Protocols documentation; Public Health; Research; Research Project Grants; Resources; Risk; Risk Reduction; Sampling; Sexual Partners; Technology; Teenagers; Testing; Text Messaging; Textiles; Time; Treatment outcome; United States; Youth; acceptability and feasibility; base; behavioral outcome; boys; cisgender; cost; cost effective; deafening; evidence base; experience; fluidity; follow-up; gender minority; girls; health disparity; healthy sexuality; high risk sexual behavior; hormone therapy; improved; intersectionality; male; member; population based; pre-exposure prophylaxis; programs; recruit; response; scale up; sex; sexual minority; skills; social; transgender; transgender women; transphobia; uptake

Estimates suggest that one in five transgender girls may be HIV positive In the face of this health disparity, the near-complete absence of gender-inclusive healthy sexuality programs is deafening. To address the lack of gender inclusive HIV prevention programming, we propose to develop and test #TranscendentHealth. Content will focus on providing girls with a panoply of risk reduction strategies, including frequent HIV/STI testing and initiating PrEP, so that they can choose options that fit best for them. Messaging will be gender affirming while increasing one’s HIV preventive information, motivation, and behavioral skills. Content will foster pride in girls’ gender identity and reduce internalized transphobia they may be experiencing. We will harness the reach and wide adoption of text messaging among youth to deliver intervention content. This national reach will increase its generalizability and translational properties. In response to RFA-OD-19-029, this proposal addresses NIMH’s high priority area of research: Intervention research to improve HIV prevention and treatment outcomes for transgender individuals that focuses on the influences of sex and gender (Strategic Goal 1.3). Specifically, we aim to: Specific Aim 1: Explore how the intersectionality of sex and gender inform the sexual decision making of transgirls 14-18 years of age (n=80). Little is known about how transgirls decide when and with whom to have sex or not, as well as how their understanding of their gender within the context of their sex influences their sexual decision-making. To explore these issues, we will conduct online focus groups. Specific Aim 2: Iteratively develop #TranscendentHealth, a gender inclusive HIV prevention program for transgirls, with ongoing input from transgirls (n=35). We will integrate findings from the focus groups into content tailored to the lived experiences of transgirls 14-18 years of age. To ensure that the messaging is affirming and acceptable, we then will conduct Content Advisory Teams (CATs), and then t a beta test to confirm the protocol. Specific Aim 3: Test the #TranscendentHealth HIV prevention program with transgirls 14-18 years of age across the United States (n=200). Our main outcome measures will be feasibility and acceptability. Behavioral outcomes will be exploratory and include those on the HIV prevention continuum41: 1) acceptability of, 2) motivation for, and 3) uptake of PrEP, if clinically indicated; and 3) HIV/STI testing and receipt of results at 3-month follow-up. Photo-verified testing also will be explored. Specific Aim 4: Understand how the intersectionality of sex and gender impact the intervention experience. We will examine whether transgirls who are undergoing gender affirming hormone therapy, have internalized transphobia, and different gender identities experience the intervention differently than other gender minority teens.

估计表明，面对这种健康，五分之一的变性女孩可能是艾滋病毒阳性的 差异，几乎完全没有性别涉及性别的健康性计划震耳欲聋。解决 缺乏性别包容性艾滋病毒预防计划，我们建议开发和测试 #transcendenthealth。内容将集中于为女孩提供降低风险策略的全面策略，包括 经常艾滋病毒/STI测试和启动准备，以便他们可以选择最适合他们的选项。消息传递 在增加一个人的艾滋病毒预防信息，动机和行为技能的同时，将肯定性别。 内容将为女孩的性别认同而自豪，并减少他们可能正在经历的内在恐惧症。 我们将利用年轻人中文本消息传递的覆盖范围和广泛采用，以提供干预内容。 这种国家覆盖范围将提高其普遍性和翻译特性。 为了回应RFA-OD-19-029，该提案涉及NIMH的高优先研究领域： 干预研究以改善跨性别者的预防艾滋病毒和治疗结果 专注于性别和性别的影响（战略目标1.3）。具体来说，我们的目标是： 特定目的1：探索性别和性别的交叉性如何为性决定提供信息 使女生14-18岁（n = 80）。关于妇女如何决定何时和与 与谁有性别，以及他们在性别中如何理解自己的性别的理解 影响他们的性决策。为了探索这些问题，我们将进行在线焦点小组。 特定目的2：迭代发展#transcendenthealth，一种预防性别的艾滋病毒 妇女妇女的程序，持续的输入来自妇女（n = 35）。我们将从焦点中整合发现 小组成于量身定制的，适合14-18岁的妇女的现场体验。确保 消息传递是肯定且可接受的，然后我们将主持内容咨询团队（CAT），然后 Beta测试以确认协议。 特定目的3：测试#transcendenthealth hiv预防计划的妇女14-18 全美的年龄（n = 200）。我们的主要结果措施将是可行性和 可接受性。行为结果将是探索性的，并包括艾滋病毒预防连续体41：1） 2）动机的可接受性和3）如果在临床上进行了摄取； 3）HIV/STI测试和 在3个月的随访中接收结果。还将探索照片验证的测试。 特定目的4：了解性别和性别的交叉性如何影响干预 经验。我们将检查正在接受性别确认骑马疗法的妇女是否已有 内在的跨性别恐惧症和不同的性别认同的经历与其他不同 性别少数青少年。