Harnessing the power of text messaging to reduce HIV incidence in adolescent males across the United States

利用短信的力量降低美国青少年男性的艾滋病毒发病率

• 批准号: 10703231
• 负责人: Michele L. Ybarra
• 金额: $ 215.47万
• 依托单位: CENTER FOR INNOVATIVE PUBLIC HEALTH RESEARCH
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-09-23 至 2026-08-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10703231
• 关键词: 18 year old; 20 year old; AIDS prevention; Adolescent; Adoption; Advertisements; Advisory Committees; Affect; African American; Attitude; Black race; Complex; Counseling; Country; Data; Development; Disparate; Disparity; Enrollment; Ensure; Epidemiology; Face; Focus Groups; HIV; HIV Infections; HIV Seronegativity; Health Status; Hispanic; Human immunodeficiency virus test; Incidence; Intervention; Latino; Latinx; Male Adolescents; Mental Health; Methods; Monitor; Motivation; Outcome Measure; Participant; Patient Self-Report; Population; Population Heterogeneity; Prevention; Prevention program; Preventive service; Program Accessibility; Protocols documentation; Public Health; Race; Research; Risk; Rural; Safety; Sampling; Services; Technology; Teenagers; Test Result; Testing; Text Messaging; United States; Youth; age group; behavior change; cisgender; cost; ethnic minority; healthy sexuality; home test; innovation; male; men; minority children; novel; pre-exposure prophylaxis; programs; racial minority; recruit; response; rural area; rural setting; secondary outcome; sexual minority; sexual minority boys; sexual minority group; sexual minority male; sexual minority youth; sexually active; social; social media; sociodemographics; uptake

Sexual minority male youth face disparate risk for HIV acquisition. Disparities are even starker for African American/Black and Hispanic sexual minority male youth, who account for 51% and 25% of new HIV infections, respectively. Youth living in southern states and in rural settings also face elevated risk for HIV acquisition. As such, access to HIV testing and counseling remains a critical component of prevention, and effectively extending these services to sexual minority male youth is a priority. The wide adoption of text messaging provides novel opportunities to go where youth “are” across socio- demographically different groups, and overcomes structural challenges of traditional interventions. Moreover, being able to access sensitive content when and where one chooses facilitates safe spaces for youth to engage with the content, which is important for those who are not ‘out’. Importantly too, reviews suggest that programs delivered via text messaging can affect complex behavior change, including HIV testing among sexual minority adolescent boys. Thus, we have the opportunity to utilize the power and reach that text messaging affords to deliver an HIV prevention program across the country to a diverse population of youth. To this end, we propose to test the impact of #GrowingUpGuy (#GUY) on new HIV infections among 13-20 year-old sexual minority male youth across the United States. #GUY will be an adaptation of the research team’s previous text messaging-based HIV prevention/healthy sexuality programs developed at the national level for sexual minority youth. Given the epidemiology of HIV infections in the United States, we plan to target youth 13-20 years of age. Because of the lack of accessible programs for younger youth, our recruitment effort will place an emphasis on those 18 years of age and younger. Sample diversity will be ensured using recruitment targets and a complex enrollment strategy that we have developed and refined over our intervention endeavors such that half will self-identify as Black/African American, Latino, and/or of mixed race; and at least 20% will be living in a rural area or southern state. Specifically, we aim to: Specific Aim 1: Finalize the GrowingUpGuy (#GUY) intervention and protocol for sexually active, HIV negative, cisgender, sexual minority boys and men up to 20 years of age across the United States. Specific Aim 1a. Adapt previous intervention content to create GrowingUpGuy (#GUY), a salient, technologically delivered HIV prevention program. Specific Aim 1b: Finalize the intervention protocol, including confirmation of HIV test results. Specific Aim 2: Test the #GUY intervention for impact on HIV incidence (n=5,000). Our main outcome measures will be: 1) OraQuick-confirmed HIV incidence; and self-reported 2) PrEP and PEP use, 3) HIV status, and 4) number of STIs. Secondary outcomes include: 1) information about and 2) motivation for uptake of PrEP; and 3) the impact of the intervention on mental health indicators.

性少数男性青年面临艾滋病毒收购的不同风险。差异甚至是明确的 非裔美国人/黑人和西班牙裔性少数族裔男性，占新艾滋病毒的51％和25％ 分别感染。居住在南部各州和粗糙环境的青年也面临着艾滋病毒的风险升高 获得。因此，获得艾滋病毒测试和咨询仍然是预防的关键组成部分，并且 有效地将这些服务扩展到性少数族裔男性青年是当务之急。 文本消息的广泛采用为您提供了新的机会，可以在社会中“年轻人”“处于”的位置 - 人口统计学不同的群体，克服了传统干预措施的结构性挑战。而且， 能够访问何时何地选择敏感内容 参与内容，这对于那些不“出去”的人很重要。同样重要的是，评论表明 通过文本消息传递提供的程序可能会影响复杂的行为改变，包括在 性少数民族青少年男孩。那就是我们有机会利用力量并掌握该文本 消息传递为在全国范围内提供艾滋病毒预防计划提供给潜水员的年轻人。 为此，我们建议测试#growingupguy（#GUY）对新艾滋病毒感染的影响 全美13-20岁的性少数男性男性青年。 #guy将是对 研究团队以前基于文本消息的基于文本消息的艾滋病毒预防/健康性计划 性少数族裔青年的国家一级。鉴于美国艾滋病毒感染的流行病学，我们计划 以13-20岁的年轻人为目标。由于缺乏针对年轻青年的可访问计划，我们的 招聘工作将重点放在18岁及以下的年龄。样本多样性将是 确保使用招聘目标和我们已经制定和完善的复杂入学策略 我们的干预措施使一半将自我识别为黑人/非裔美国人，拉丁裔和/或混合 种族;至少有20％将生活在崎rough的地区或南部州。具体来说，我们的目标是： 特定目标1：最终确定性活动的growingupguy（#guy）干预和协议， 在美国，艾滋病毒负面，sisgender，性少数族裔男孩和男性。 特定目标1a。调整以前的干预内容来创建rawingupguy（#guy），一个明显的 从技术上讲，预防艾滋病毒的计划。 具体目标1B：最终确定干预方案，包括确认HIV测试结果。 具体目标2：测试#GUY干预对HIV事件的影响（n = 5,000）。我们的主要 结果指标将是：1）Oraquick确认的HIV事件；自我报告2）PREP和PEP使用，3） HIV状态和4）性传播疾病数量。次要结果包括：1）有关和2）动机的信息 吸收准备； 3）干预对心理健康指标的影响。