Administrative Core

行政核心

• 批准号: 10226344
• 负责人: JOHN J FOXE
• 金额: $ 21.4万
• 依托单位: UNIVERSITY OF ROCHESTER
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-08-01 至 2025-05-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10226344
• 关键词: Advisory Committees; Advocacy; Animal Behavior; Architecture; Basic Science; Brain; Budgets; Charge; Clinical; Clinical Research; Communities; Community Health Education; Competence; Consultations; Core Facility; Development; Disease; Educational Activities; Educational workshop; Ensure; Environment; Evaluation; Event; Evolution; Eye; Family; Fostering; Funding; Funding Agency; Future; Grant; Heart; High Performance Computing; Human; Informatics; Infrastructure; Intellectual and Developmental Disabilities Research Centers; International; Kinesiology; Knowledge; Leadership; Linguistics; Mink; Mission; Modernization; Morals; Newsletter; Parents; Pathologic; Persons; Phenotype; Policies; Policy Maker; Postdoctoral Fellow; Quality Control; Rare Diseases; Reporting; Research; Research Activity; Research Infrastructure; Research Personnel; Research Project Grants; Resources; Science; Scientific Advances and Accomplishments; Scientist; Series; System; Technical Expertise; Techniques; Technology; Training; Translating; Translational Research; Universities; Vision; Work; archive data; autism spectrum disorder; base; cellular imaging; community engagement; cost effectiveness; cultural competence; data archive; data sharing; density; design; disability; diversity and inclusion; early life exposure; early life stress; experience; federal policy; high risk; innovation; insight; member; molecular imaging; multisensory; neurodevelopment; neuroimaging; neuroinflammation; neurophysiology; open data; operation; outreach; postdoctoral investigator; pre-doctoral; predoctoral investigator; prevent; professor; programs; recruit; social media; symposium; technology development

Project Summary: The Administrative Core (ADM) of this new University of Rochester (UR) IDDRC application serves as the main coordination hub of a fully integrated system of four scientific cores that support the crucial work of 105 UR-IDDRC investigators currently prosecuting 202 basic, translational and clinical research projects in the domain of IDD research. These cores are: Human Phenotyping & Recruitment (HPR); Translational Neuroimaging & Neurophysiology (TNN); Cell & Molecular Imaging (CMI); and Animal Behavior and Neurophysiology (ABN). The ADM Core brings together two international leaders in the field of IDD research, Professors John Foxe and Jonathan Mink, both with a wealth of complementary leadership experience, to coordinate and prosecute this effort. In consultation with the UR-IDDRC community, they have formulated a clear and progressive mission of excellence in IDD research, one that places the people we serve, those with an IDD, at the heart of our Center, and one that promotes equity, inclusion, diversity, and cultural/linguistic competence. The ADM leadership has identified five thematic research clusters that serve to coalesce our portfolio into a coherent well-articulated IDD program, and around which we will build our future. These are: (1) Rare & Orphaned Diseases of Neurodevelopment; (2) Parental Stress & Early Life Exposure as Determinants of Brain Development; (3) Neuroinflammatory Mechanisms in Pathological Brain Development; (4) Autism Spectrum Disorder; and (5) Multisensory & Sensorimotor Integration. The ADM coordinates a substantial pilot grant program, supported through extensive philanthropic efforts and substantial University support, distributing $400,000 per annum in a highly competitive program designed to promote high-risk high- return IDD projects. We have set in place an innovative system of educational activities for pre- and post- doctoral trainees, and a substantial dissemination effort that includes multiple online social media outlets (with closed captioning in Spanish, and ASL translators at live events), an effort that has been specifically designed to be consumable by the public. The ADM coordinates a major data archiving and sharing effort across the Cores, interfacing with the UR CTSI and leveraging our state-of-the-art Bio-Lab Informatics System (BLIS). The Core has established reportage and systematic assessments that continuously scrutinize and evaluate the functioning of the center, ensuring that efficiency and cost-effectiveness are maintained at the highest levels and that the Cores evolve to be fully responsive to changes in technology and systems. The ADM is supported by five key advisory committees that provide crucial input regarding ongoing functioning of the center. These are: (a) The Executive Committee; (b) The External Advisory Board; (c) The Parent and Community Advisory Board; (d) The Internal Advisory Board; and (e) The Core Facilities Management Committee. We stand committed to a clear-eyed purpose, that through our science, we will endeavor each and every day to remove impediments facing people with IDD that prevent them from living the healthiest, most fulfilling lives possible.

项目摘要：罗切斯特新大学（UR）IDDRC的行政核心（ADM） 应用是一个支持四个科学核心的完全集成系统的主要协调中心 目前有105个UR-IDDRC调查人员的关键工作目前起诉202个基本，翻译和临床 IDD研究领域的研究项目。这些核心是：人类表型和招聘（HPR）； 翻译神经影像学和神经生理学（TNN）；细胞和分子成像（CMI）；和动物行为 和神经生理学（ABN）。 ADM核心汇集了IDD领域的两名国际领导人 研究教授约翰·福克斯（John Foxe）和乔纳森·梅克（Jonathan Mink）都有丰富的互补领导 经验，协调和起诉这项工作。在与UR-IDDRC社区协商时，他们有 制定了一个明确而渐进的IDD研究使命，这是我们的人民 在我们中心的核心中提供服务，并促进公平，包容性，多样性和 文化/语言能力。 ADM领导层确定了五个主题研究集群 将我们的投资组合结合成一个连贯的良好定义的IDD计划，我们将建立我们的未来。 这些是：（1）神经发育的罕见和孤立疾病； （2）父母的压力和早期生活暴露为 大脑发育的决定因素； （3）病理大脑发育中的神经炎症机制； （4）自闭症谱系障碍； （5）多感官和感觉运动集成。 ADM协调 大量的试点赠款计划，通​​过广泛的慈善努力和实质性大学支持 支持，在一项旨在促进高风险高风险的计划的竞争激烈的计划中，每年分配40万美元 返回IDD项目。我们已经建立了一种创新的教育活动体系，用于前后 博士学员，以及包括多个在线社交媒体的大量传播工作（有 现场活动中的西班牙语和ASL翻译人员的封闭字幕）是专门设计的。 由公众消费。 ADM协调主要的数据归档和共享努力 核心与Ur CTSI接口并利用我们最先进的Bio-LAB信息学系统（BLIS）。 核心已经建立了报告和系统评估，不断审查和评估 中心的功能，确保效率和成本效益保持在最高水平 核心演变成对技术和系统变化的完全响应。 ADM受到支持 由五个关键咨询委员会提供了有关中心正在进行运作的关键意见。这些 是：（a）执行委员会； （b）外部顾问委员会； （c）父母和社区咨询 木板; （d）内部顾问委员会； （e）核心设施管理委员会。我们站着 致力于清晰的目的，通过我们的科学，我们将每天努力去除 患有IDD的人面临的障碍阻止他们过着最健康，最充实的生活。