Consortium-Wide Coordinating Core

联盟范围内的协调核心

• 批准号: 10194365
• 负责人: MICHAEL L TERRIN
• 金额: $ 20.4万
• 依托单位: UNIVERSITY OF MARYLAND BALTIMORE
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-06-16 至 2025-05-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10194365
• 关键词: Acute; Advanced Development; Animal Model; Animals; Archives; Basic Science; Biocompatible Materials; Bioinformatics; Biological Markers; Biometry; Businesses; Calendar; Cellular biology; Collaborations; Communication; Communities; Computer software; Data; Data Coordinating Center; Documentation; Educational Activities; Educational Materials; Equipment; Event; Funding; General Population; Information Centers; Information Dissemination; Infrastructure; Link; Medical center; Methods; Modeling; Monitor; National Heart, Lung, and Blood Institute; National Institute of Allergy and Infectious Disease; Nature; Pilot Projects; Procedures; Protocols documentation; Publications; Radiation; Radiation Syndromes; Radiobiology; Reagent; Research; Research Personnel; Resources; Running; Schedule; Specimen; System; Time; Training and Education; Translational Research; U-Series Cooperative Agreements; United States National Institutes of Health; Update; data exchange; data sharing; experience; innovation; interest; medical countermeasure; meetings; programs; radiation countermeasure; response; social media; stem cells; symposium; web page; web site

Abstract We propose to meet the need of the NIAID Centers for Medical Countermeasures Against Radiation Consortium (CMCRC) for 1) administrative infrastructure to organize interactions and facilitate collaboration among CMCRC investigators, 2) oversight of programs using funds to stimulate Pilot Studies, 3) timely sharing of CMCRC-generated data, biomarkers, (animal) models and reagents among CMCRC investigators and with the research community, and, 4) biostatistics and bioinformatics support, in response to AI-10-012, with staff who bring years of experience working along similar lines in the NHLBI Progenitor Cell Biology Consortium (PCBC) Administrative Coordinating Center (ACC) and the Progenitor Cell Translational Consortium (PCTC) Administrative Coordinating Center (ACC). The proposed investigators and staff have extensive experience in coordinating centers, organization of meetings, collaborative research under cooperative agreements, consortium infrastructure, web site, communications, monitoring and documentation. We will adapt and advance our infrastructure (hardware, software, web sites and links, offices, office equipment and staff) in place for the PCBC ACC and PCTC ACC to extend to the CMCRC resulting in an immediate, running start for the CMCRC Consortium-wide Coordinating Center (CCC) on day one. We will proceed to expand the functions of the extant infrastructure to additional, innovative use of social media to reach all corners of the CMCRC community and out to the broader research community. The CMCRC Consortium-wide Coordinating Center will follow procedures it has established and is using for other NIH- supported coordinating centers to perform administrative tasks necessary to conduct consortium meetings and conference calls, prepare agendas and minutes, administer funds for training and education and support a web site for communications, transmission of data, information and descriptions of methods (e.g., protocols) and requests for reagents, biomaterials and (animal) models to be shared. Our proposal is both highly efficient and innovative because of the expertise and experience of our investigators, the uninterruptable nature of their backup for each other and the uninterruptable nature of the systems we will extend and update from the PCBC and PCTC to the CMCRC. The channeling of resources to translational research, basic research necessary to support translational research and the extension of our infrastructure through social media will be substantial.

抽象的 我们建议满足NIAID中心对辐射的医疗对策的需求 联盟（CMCRC）用于1）行政基础设施以组织互动并促进协作 在CMCRC调查人员中，2）对使用资金刺激试点研究的计划进行监督，3）及时共享 CMCRC生成的数据，生物标志物，（动物）模型和试剂中的CMCRC研究者以及与 研究界，以及4）生物统计学和生物信息学支持，以应对AI-10-012 在NHLBI祖细胞生物联盟中，他们带来了多年的经验 （PCBC）行政协调中心（ACC）和祖细胞翻译联盟（PCTC） 行政协调中心（ACC）。拟议的调查人员和员工在 协调中心，会议组织，合作协议下的合作研究， 财团基础架构，网站，通信，监视和文档。 我们将适应并推进基础架构（硬件，软件，网站和链接，办公室，办公室 设备和人员）适当的PCBC ACC和PCTC ACC扩展到CMCRC，导致 第一天，CMCRC整个联盟协调中心（CCC）的立即开始。我们将 继续将现有基础架构的功能扩展到社交媒体的其他创新使用 到达CMCRC社区的所有角落，然后进入更广泛的研究社区。 CMCRC 整个财团的协调中心将遵循其已建立的程序，并用于其他NIH- 支持协调中心，以执行进行财团会议所必需的行政任务和 电话会议，准备议程和会议记录，管理培训和教育资金，并支持网络 用于通信，传输数据，信息和描述的网站（例如协议）和 要共享试剂，生物材料和（动物）模型的请求。 由于我们的专业知识和经验，我们的建议既高效又创新 调查人员，互相备份的不间断性质，以及 我们将从PCBC和PCTC扩展并更新到CMCRC。将资源引导到 翻译研究，支持翻译研究所必需的基础研究和我们的扩展 通过社交媒体的基础设施将是巨大的。