PCTC Administrative Coordinating Center

PCTC行政协调中心

• 批准号: 9486998
• 负责人: MICHAEL L TERRIN
• 金额: $ 114.54万
• 依托单位: UNIVERSITY OF MARYLAND BALTIMORE
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-09-20 至 2023-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9486998
• 关键词: Advisory Committees; Agreement; Authorization documentation; Award; Basic Science; Biocompatible Materials; Bioinformatics; Biological Sciences; Budgets; Cell Line; Cell Therapy; Cellular biology; Collaborations; Committee Members; Communication; Communities; Computer software; Consultations; Data; Documentation; Electronic Mail; Equipment; Evaluation; Funding; Goals; Heart Diseases; Hematological Disease; Individual; Institution; Interdisciplinary Study; Interval training; Link; Lung diseases; Methods; Modeling; Monitor; National Heart, Lung, and Blood Institute; Nature; Parents; Participant; Pilot Projects; Postdoctoral Fellow; Preparation; Principal Investigator; Procedures; Progress Reports; Protocols documentation; Reagent; Research; Research Infrastructure; Research Personnel; Research Proposals; Resources; Role; Running; Scientist; Secure; Source; Stem cells; System; Telephone; Time; Training Programs; Translating; Translational Research; U-Series Cooperative Agreements; United States Food and Drug Administration; Update; Work; base; disease mechanisms study; experience; food preparation; graduate student; improved; innovation; meetings; novel therapeutics; programs; repository; research and development; response; skill acquisition; social media; symposium; training opportunity; web page; web site

Abstract To meet the need of the NHLBI Progenitor Cell Translational Consortium (PCTC) for 1)administrative infrastructure to organize interactions and facilitate collaborations between PCTC investigators, 2) oversight of programs of programs using set-aside funds to stimulate collaborative research and skills development, 3) timely sharing of PCTC-generated data and reagents among PCTC investigators and with the research community, and 4) for facilitated access to expertise for preparation of U.S. Food and Drug Administration (FDA) IND and IDE applications, we propose a PCTC Coordinating Center in response to RFA-HL-16-022, staffed by individuals who bring years of experience working along similar lines in the NHLBI Progenitor Cell Biology Consortium (PCBC) Administrative Coordinating Center (ACC); they have extensive experience in coordinating centers, organization and conduct of solicitation/review/ and award of proposals for research or skills development, FDA procedures for preparation of IND and IDE applications, collaborative research under cooperative agreements, consortium infrastructure, web site, communications, monitoring and documentation. We will adapt and advance our infrastructure (hardware, software, web sites and links, offices, office equipment and staff) in place for the PCBC ACC to extend to the PCTC resulting in an immediate, running start for the PCTC on day one. We will proceed to expand the functions of the extant infrastructure to additional, innovative use of social media to reach all corners of the PCTC community and out to the broader research community. We will continue the PCBC procedures for Skills Development support as well as support of solicitation/review/and award of pilot and ancillary/collaborative studies of which there have been 31 ancillary/collaborative study awards and 14 pilot study awards resulting from over 200 applications and 26 "jump start (small post-doctoral fellow pilot study)" awards from 78 applications. Our proposal is both highly efficient and innovative because of the expertise and experience of our investigators, the uninterruptable nature of their backup for each other and the uninterruptable nature of the systems we will extend and update from the PCBC to the PCTC. The PCBC ACC was able to accomplish all that it did with less than 3% of the consortium budget spent outside of the research hubs, cores and their projects. The channeling of resources to translational research, basic research necessary to support translational research and skills development that building on the PCBC infrastructure and the additional extension of our infrastructure through social media will be substantial.

抽象的 满足NHLBI祖细胞转化联盟（PCTC）的需求1） 组织互动并促进PCTC调查人员之间的合作，2）监督 使用固定资金的计划计划刺激协作研究和技能发展的计划，3） 及时共享PCTC生成的数据和PCTC研究人员中的试剂以及研究 社区和4）促进获得美国食品和药物管理局的专业知识的机会 （FDA）IND和IDE应用程序，我们提出了一个响应RFA-HL-16-022的PCTC协调中心， 由在NHLBI祖细胞中带来多年经验的个人组成的个人 生物联盟（PCBC）行政协调中心（ACC）；他们有丰富的经验 协调中心，组织和行为的招标/审查/授予研究或 技能开发，FDA程序准备IND和IDE应用程序，协作研究 合作协议，财团基础设施，网站，通信，监视和文档。 我们将适应并推进基础架构（硬件，软件，网站和链接，办公室，办公室 设备和人员）适当的是PCBC ACC扩展到PCTC，导致立即开始运行 对于第一天的PCTC。我们将继续将现有基础架构的功能扩展到附加 社交媒体的创新使用来到达PCTC社区的所有角落，并进行更广泛的研究 社区。我们将继续采用PCBC程序以进行技能发展支持以及支持 征集/审查/奖励试点和辅助/协作研究的奖励已有31 辅助/协作研究奖和14个试点研究奖，由200多个申请和26个 “跳跃开始（小型博士后同学研究）”来自78个应用程序。 由于我们的专业知识和经验，我们的建议既高效又创新 调查人员，互相备份的不间断性质，以及 我们将从PCBC扩展并更新到PCTC。 PCBC ACC能够完成所有工作 它在研究枢纽，核心及其之外花费了不到3％的财团预算 项目。将资源转向转化研究，支持支持的基础研究 在PCBC基础架构和其他的转化研究和技能开发以及其他 通过社交媒体扩展我们的基础设施将是大量的。