Core C: Data Management & Statistical

核心C：数据管理

• 批准号: 10164696
• 负责人: CHENGJIE XIONG
• 金额: $ 27.56万
• 依托单位: WASHINGTON UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-05-15 至 2025-04-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10164696
• 关键词: Alzheimer' s Disease; Collaborations; Consult; Consultations; Data; Data Analyses; Data Set; Databases; Informatics; Institutes; Lead; Methodology; Progress Reports; Quality Control; Reproducibility; Research; Research Personnel; Research Project Grants; Resources; Statistical Methods; Techniques; Time; Work; data management; data submission; database design; design; novel; statistics

Core C: Data Management and Statistics Project Summary The Data Management and Statistics Core (DMSC) provides data management support and statistical consultation to facilitate research and sharing of other Cores/Components and research projects utilizing resources of the ADRC, as well as both local and collaborative analyses between and among AD Centers and with NACC. We aim: (1) to manage the ADRC-wide database, from the design of forms (if necessary) to data entry, to database quality control (QC), and finally to the distribution of analysis data sets to investigators and for progress reporting, by interacting closely with all Cores/Components that generate data; (2) to work closely with the WU Institute of Informatics (I2) to make data collected by ADRC Cores available to all ADRC investigators through an interface between REDCap and SAS; (3) to collaborate with NACC to make smooth and timely data submissions (e.g., the Uniform Data Set); (4) to lead and consult on the statistical design and data analyses of all ADRC projects with respect to the application of appropriate statistical and methodological techniques, and to develop novel statistical methods tackling emerging analytic challenges from ADRC Cores; (5) to promote reproducible research in the ADRC from database integrity to analytic integrity; (6) to facilitate local analyses and collaborations between and among ADCs and with NACC.

核心C：数据管理和统计项目摘要 数据管理和统计核心（DMSC）提供数据管理支持和统计 咨询以促进利用其他核心/组件和研究项目的研究和共享 ADRC的资源以及广告中心之间的本地和协作分析以及 与NACC。我们的目标： （1）管理ADRC范围的数据库，从表单的设计（如有必要）到数据输入，到数据库 质量控制（QC），最后是分析数据集向研究者的分布和进步 报告，通过与生成数据的所有内核/组件紧密互动； （2）与WU信息学研究所（I2）紧密合作，以使ADRC核心收集的数据可用 通过REDCAP和SAS之间的接口给所有ADRC研究人员； （3）与NACC合作以进行平稳，及时的数据提交（例如，统一数据集）； （4）领导并咨询所有ADRC项目的统计设计和数据分析 应用适当的统计和方法学技术，并开发新的统计 解决ADRC核心的新兴分析挑战的方法； （5）从数据库完整性到分析完整性促进ADRC中可重复的研究； （6）促进ADC和NACC之间和与NACC之间的本地分析和合作。