Engagement in Longevity and Medicine (ELM)

参与长寿与医学 (ELM)

• 批准号: 10163111
• 负责人: JOSHUA CHODOSH
• 金额: $ 92.93万
• 依托单位: NEW YORK UNIVERSITY SCHOOL OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-09-15 至 2023-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10163111
• 关键词: Address; Adult; Age; Aging; Alzheimer' s disease related dementia; Asians; Behavioral Research; Biomedical Research; Businesses; Censuses; Chronic; Chronic Disease; Clinic; Clinical; Clinical Research; Clinical Trials; Cognitive; Communication; Communities; Community Health; Community Health Aides; Community Networks; Competence; Complex; Computerized Medical Record; Consent; Country; Development; Diagnosis; Early Diagnosis; Education; Elderly; Electronic Health Record; Face; Family; Federally Qualified Health Center; Future; Goals; Growth; Health; Health Personnel; Healthcare; Hospitals; Human Subject Research; Immigrant; Impaired cognition; Impairment; Individual; Infrastructure; Intervention; Knowledge; Latino; Limited English Proficiency; Logistics; Longevity; Low income; Medicine; Methods; Minority; Modeling; Municipalities; National Institute on Aging; New York; New York City; Older Population; Outcomes Research; Participant; Patient Recruitments; Patient-Focused Outcomes; Patients; Plant Roots; Population; Population Heterogeneity; Population Research; Population trends; Prevention; Provider; Recording of previous events; Registries; Research; Research Infrastructure; Research Personnel; Science; Sensory; Social Work; System; Technology; Testing; Training; Training Programs; Treatment Protocols; United States; United States Department of Veterans Affairs; Universities; Ursidae Family; Work; age group; aging population; base; community engagement; community partnership; community setting; disparity reduction; ethnic minority population; experience; health communication; health disparity; health literacy; innovation; interest; member; multiple chronic conditions; novel; racial minority; recruit; repository; retention rate; service providers; simulation

PROJECT SUMMARY/ABSTRACT The goal of this project is to establish a centralized research infrastructure that harnesses New York University (NYU) Langone Health’s clinical and community partnerships throughout New York City to strengthen and advance the science of community engagement, recruitment and retention in aging and Alzheimer’s and related dementia (ADRD) research. Despite the tremendous growth in the older adult and elderly population, particularly among racial and ethnic minorities, these individuals are underrepresented in clinical research. Older age participants face challenges that differ from younger age populations in engagement, recruitment and retention in human subjects research. These include concerns about chronic disease complexities, mobility limitations, and cognitive and sensory impairments that may limit access to research opportunities or capacity to consent. As a result, the evidence of what works in healthcare interventions is less generalizable to older populations, particularly for minority and low-income communities despite the recognition of the disproportionate burden of health disparities among these communities. To address these concerns, the NYU Engagement in Longevity and Medicine (ELM) Research Collaborative will evaluate and disseminate best practices in engaging, recruiting and retaining older populations, stimulate the development and testing of innovative community-engaged and technology-based approaches to participant recruitment in clinical and community settings, and strengthen communication and messaging strategies tailored to diverse aging research populations that are inclusive of ADRD communities and representative of the National Institute on Aging’s priority populations. To increase engagement, recruitment, and retention of older age subjects into aging and ADRD research, the NYU ELM Research Collaborative will: 1) establish a centralized infrastructure including community members, clinical researchers, and patient and family stakeholders in aging and ADRD research; 2) analyze and evaluate what is currently known about successful strategies and challenges in recruitment and retention; 3) develop innovative approaches for education and engagement using electronic health record systems and community navigators rooted in the community health worker model; 4) build and deploy a novel training program for research teams using simulation with actors as potential subjects; and 5) develop a broad-based research registry of interested potential subjects reflective of the diversity of the older adult US population. This study will provide immediate benefit to ongoing aging and ADRD clinical trials and substantial support to future trials.

项目摘要/摘要 该项目的目标是建立一个利用纽约大学的集中研究基础设施 （NYU）Langone Health在整个纽约市的临床和社区伙伴关系，以加强和 推进社区参与，招募和保留的科学，并与阿尔茨海默氏症及相关 痴呆（ADRD）研究。尽管老年人和老年人口的增长巨大，尤其是 在种族和少数民族中，这些人在临床研究中的人数不足。年龄较大 参与者面临与年轻年龄人群在参与，招聘和保留方面不同的挑战 在人类受试者研究中。这些包括对慢性疾病复杂性，流动性限制， 以及可能限制获得研究机会或同意能力的认知和感觉障碍。 结果，证明医疗干预措施中有效的作用的证据不太概括到较老的人群中， 尽管认识到少数族裔和低收入社区，尽管承认 这些社区之间的健康差异。 为了解决这些问题，NYU参与长寿与医学（ELM）研究合作 评估和传播在参与，招募和保留较老人群的最佳实践，刺激 开发和测试创新的社区参与和基于技术的方法的参与 在临床和社区环境中招募，并加强量身定制的沟通和消息传递策略 对于包含ADRD社区并代表国家的潜水衰老研究人群 老化的优先人口研究所。 为了增加年龄较大的受试者的参与，招募和保留在衰老和ADRD研究中， 纽约大学ELM研究合作社：1）建立一个集中的基础设施，包括社区成员， 临床研究人员，以及衰老和ADRD研究的患者和家庭利益相关者； 2）分析和评估 目前，关于招募和保留方面的成功策略和挑战的了解； 3）发展 使用电子健康记录系统和社区的教育和参与的创新方法 植根于社区卫生工作者模型的导航员； 4）建立和部署一个新颖的培训计划 使用与演员一起模拟的研究团队作为潜在主题； 5）开发基于广泛的研究 有趣的潜在主题的注册表反映了美国老年人的多样性。这项研究会 为正在进行的衰老和ADRD临床试验提供直接利益，并为将来的试验提供大量支持。