Lymph node metastasis of oral cancer with 18FDG-PET

18FDG-PET观察口腔癌淋巴结转移

基本信息

批准号：
09671929
负责人：
SHOZUSHIMA Masanori
金额：
$ 2.18万
依托单位：
Iwate Medical University
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (C)
财政年份：
1997
资助国家：
日本
起止时间：
1997 至 1999
项目状态：
已结题

来源：
https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-09671929/
关键词：
FDG PET head and neck cancer lymphnode metastasis Image diagnosis リンパ節転移頭頸部悪性腫瘍口腔癌

项目摘要

The image fusion of PET and CT from the head and neck region was performed with the use of external markers in 7 patients with squamous cell carcinoma. The purpose of this study was to examine a resultant error and clinical usefulness of the image fusion.Patients had primary lesion of the tongue, the maxillary gingiva or the maxillary sinus. All patients underwent PET with FDG and CT to detect tumor sites. Of these 7 patients, 6 cases were also pronounced regional lymph node metastasis to the neck from the diagnostic images and the clinical observation. To ensure anatomical detail of the PET images, small radioactive markers were placed on the philtrum and below both earlobes. The PET image and CT image were then overlapped each other on a computer.The image fusion of PET and CT was achieved in all patients. The superposition error of this method was examined between PET and CT images. The accuracy of fit measured as the mean distance between PET and CT image was in the range of 2 - 5 mm. PET-CT superimposed images produced localization of tumor FDG uptake increase and FDG uptake to palatine tonsil were also localized.The marker system described here for the alignment of PET and CT images can be used on a routine bases without the invasive fixation of external markers, improve the management and follow up of patients with head and neck carcinoma.

在7种鳞状细胞癌患者中使用外部标记，从头到尾进行了PET和CT的图像融合。这项研究的目的是检查图像融合的结果误差和临床实用性。患者患有舌头，上颌牙龈或上颌窦的主要病变。所有患者接受了FDG和CT的PET来检测肿瘤部位。在这7例患者中，也有6例明显从诊断图像和临床观察到颈部的区域淋巴结转移。为了确保PET图像的解剖学细节，将小的放射性标记放在Philtrum和两个耳垂下方。然后在计算机上彼此重叠PET图像和CT图像。所有患者均达到了PET和CT的图像融合。在PET和CT图像之间检查了该方法的叠加误差。拟合的准确性在PET和CT图像之间的平均距离为2-5 mm。 PET-CT叠加的图像在肿瘤FDG摄取的摄入量增加和对palatine扁桃体的FDG摄取也被定位。此处所描述的标记系统可用于对齐PET和CT图像，可以在常规碱基上使用，而无需侵入性的固定固定，可以改善外脑，改善管理和跟踪头颈部癌症患者。