EVALUATION OF THE MUTAGENICITY IN THE ENVIRONMENTAL WATER

环境水中突变性的评估

• 批准号: 07308041
• 负责人: HAYATSU Hikoya
• 金额: $ 3.14万
• 依托单位: OKAYAMA UNIVERSITY
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (B)
• 财政年份: 1995
• 资助国家: 日本
• 起止时间: 1995 至 1996
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-07308041/
• 关键词: ADSORBENT FOR MUTAGEN; BLUE CHITIN COLUMN; CARCINOGENS IN ENVIRONMENTAL WATER; BIOLOGICAL MONITORING; ENVIRONMENTAL POLLUTION; 健康影響; 生物学的環境モニタリング; 環境汚染; ブルーレイヨンカラム濃縮法

Using the blue chitin column technique, mutagens in the water of two rivers (Katsura river in Kyoto, and Asahi river in Okayama), were monitored. The results were compared with these found by already available method, the XAD-2 resin concentration technique. As a result, the blue chitin method proved to be 2 times more efficient in concentrating the mutagens. The blue rayon hanging technique was used to monitor mutagens in lakes in the Fukuoka area and the results showed that the lakes that showed no high COD values gave positive mutagenic responses. In conclusion, the blue chitin column and blue rayon hanging methods have been firmly established as techniques for monitoring mutagens in the environmental waters.

利用蓝色甲壳素柱技术，对两条河流（京都的桂川和冈山的旭川）水中的诱变剂进行了监测。将结果与现有方法（XAD-2 树脂浓缩技术）发现的结果进行比较。结果证明，蓝色甲壳素方法浓缩诱变剂的效率提高了 2 倍。采用蓝色人造丝悬挂技术对福冈地区湖泊的诱变剂进行监测，结果显示，COD值不高的湖泊呈现阳性诱变反应。总之，蓝色甲壳素柱和蓝色人造丝悬挂方法已被牢固确立为监测环境水域诱变剂的技术。

项目成果

堀川和美: "Evaluation of mutagenicity of complex mixture of nitroarenes using mouse micronuclei test" J.Toxicological & Environmental Chemistry. 54. 161-165 (1996)

Kazumi Horikawa：“使用小鼠微核测试评估硝基芳烃复杂混合物的致突变性”J.Toxicological & Environmental Chemistry 54. 161-165 (1996)。

S.Kira, Y.Nogami, K.Taketa, and H.Hayatsu: "Comparison of techniques for monitoring water-borne polycyclic mutagens : efficiency of blue rayon, Sep-Pak C18, and a biota, Corbicula, in concentrating benzo (a) pyrene in a model water system." Bull.Environ.C

S.Kira、Y.Nogami、K.Taketa 和 H.Hayatsu：“监测水性多环诱变剂的技术比较：蓝色人造丝、Sep-Pak C18 和生物群 Corbicula 在浓缩苯并（a

H.Hayatsu,et al.: "A short column technique for concentrating mutagen/carcinogens having polycyclic structures." Analytical Biochemistry. (in press).

H.Hayatsu 等人：“一种用于浓缩具有多环结构的诱变剂/致癌物的短柱技术。”

S.Kira, Taketa, T.Nogami, H.Hayatsu: "A simple technique for monitaring mutagenicity and benzo (a) pyrene content in mussels and their ambient water." Environ.Toxicol.Water Qual.10. 167-172 (1995)

S.Kira、Taketa、T.Nogami、H.Hayatsu：“一种监测贻贝及其环境水中致突变性和苯并 (a) 芘含量的简单技术。”

中室克彦: "Disinfection by-products in the chlorination of organic nitrogen compounds : By-products from kynurenine" Chemoshere. 33. 1425-1433 (1996)

Katsuhiko Nakamuro：“有机氮化合物氯化过程中的消毒副产物：犬尿氨酸的副产物”Chemoshere 33. 1425-1433 (1996)。