EVALUATION OF THE MUTAGENICITY IN THE ENVIRONMENTAL WATER

环境水中突变性的评估

• 批准号: 07308041
• 负责人: HAYATSU Hikoya
• 金额: $ 3.14万
• 依托单位: OKAYAMA UNIVERSITY
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (B)
• 财政年份: 1995
• 资助国家: 日本
• 起止时间: 1995 至 1996
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-07308041/
• 关键词: ADSORBENT FOR MUTAGEN; BLUE CHITIN COLUMN; CARCINOGENS IN ENVIRONMENTAL WATER; BIOLOGICAL MONITORING; ENVIRONMENTAL POLLUTION; 健康影響; 生物学的環境モニタリング; 環境汚染; ブルーレイヨンカラム濃縮法

Using the blue chitin column technique, mutagens in the water of two rivers (Katsura river in Kyoto, and Asahi river in Okayama), were monitored. The results were compared with these found by already available method, the XAD-2 resin concentration technique. As a result, the blue chitin method proved to be 2 times more efficient in concentrating the mutagens. The blue rayon hanging technique was used to monitor mutagens in lakes in the Fukuoka area and the results showed that the lakes that showed no high COD values gave positive mutagenic responses. In conclusion, the blue chitin column and blue rayon hanging methods have been firmly established as techniques for monitoring mutagens in the environmental waters.

使用蓝色几丁质柱技术，监测了两条河水（京都的Katsura河和冈山的asahi河）的诱变剂。将结果与已经可用的方法（XAD-2树脂浓度技术）进行了比较。结果，蓝色几丁质方法在浓缩诱变剂方面的效率高2倍。蓝色人造丝悬挂技术用于监测福冈地区湖泊中的诱变剂，结果表明，没有显示高COD值的湖泊产生阳性诱变反应。总之，蓝色几丁质柱和蓝色人造丝悬挂的方法已被牢固地确定为监测环境水域中诱变剂的技术。

项目成果

堀川和美: "Evaluation of mutagenicity of complex mixture of nitroarenes using mouse micronuclei test" J.Toxicological & Environmental Chemistry. 54. 161-165 (1996)

Kazumi Horikawa：“使用小鼠微核测试评估硝基芳烃复杂混合物的致突变性”J.Toxicological & Environmental Chemistry 54. 161-165 (1996)。

S.Kira, Y.Nogami, K.Taketa, and H.Hayatsu: "Comparison of techniques for monitoring water-borne polycyclic mutagens : efficiency of blue rayon, Sep-Pak C18, and a biota, Corbicula, in concentrating benzo (a) pyrene in a model water system." Bull.Environ.C

S.Kira、Y.Nogami、K.Taketa 和 H.Hayatsu：“监测水性多环诱变剂的技术比较：蓝色人造丝、Sep-Pak C18 和生物群 Corbicula 在浓缩苯并（a

H.Hayatsu,et al.: "A short column technique for concentrating mutagen/carcinogens having polycyclic structures." Analytical Biochemistry. (in press).

H.Hayatsu 等人：“一种用于浓缩具有多环结构的诱变剂/致癌物的短柱技术。”

H.Hayatsu, Y.Tanaka and T.Hayatsu: "Non-covalent binding of carcinogenic heterocyclic amines to polynucleotides." Collet.Czech.Chem.Commun.Special Issue. 61. 250-252 (1996)

H.Hayatsu、Y.Tanaka 和 T.Hayatsu：“致癌杂环胺与多核苷酸的非共价结合。”

S.Kira, Taketa, T.Nogami, H.Hayatsu: "A simple technique for monitaring mutagenicity and benzo (a) pyrene content in mussels and their ambient water." Environ.Toxicol.Water Qual.10. 167-172 (1995)

S.Kira、Taketa、T.Nogami、H.Hayatsu：“一种监测贻贝及其环境水中致突变性和苯并 (a) 芘含量的简单技术。”