Interfacial Studies of Nanoparticulate Dendrimers for Improved BioPharmaceutical Application

用于改进生物制药应用的纳米颗粒树枝状聚合物的界面研究

• 批准号: LP0455268
• 负责人: Prof Clive Prestidge
• 金额: $ 26.91万
• 依托单位: University of South Australia
• 依托单位国家: 澳大利亚
• 项目类别: Linkage Projects
• 财政年份: 2004
• 资助国家: 澳大利亚
• 起止时间: 2004-09-10 至 2007-09-10
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/LP0455268
• 关键词: Interfacial; Studies; Nanoparticulate; Dendrimers; Improved

Dendrimers are a novel class of nanoparticles with exciting potential as pharmaceuticals for the prevention of major disease states, e.g. viral and cancer. A colloid and interfacial chemistry approach will be employed to develop an understanding of the mechanisms for the solution to cell transport processes and for optimisation of formulation strategies for delivery vehicles. Significant advances in the development of novel pharmaceutical products will result, with significant social and economic benefits nationally and internationally.

树枝状聚合物是一类新型的纳米颗粒，具有令人兴奋的潜力作为预防主要疾病状态的药物，例如病毒和癌症。 将采用一种胶体和界面化学方法来发展解决细胞运输过程的机制以及优化用于输送车辆的配方策略的机制。 新型药品的开发发展将取得重大进展，并在国内和国际上具有重大的社会和经济利益。