A Physicochemical Approach for Optimizing Drug Delivery from BioSilicon

优化 BioSilicon 药物输送的物理化学方法

• 批准号: LP0562379
• 负责人: Prof Clive Prestidge
• 金额: $ 30.36万
• 依托单位: University of South Australia
• 依托单位国家: 澳大利亚
• 项目类别: Linkage Projects
• 财政年份: 2005
• 资助国家: 澳大利亚
• 起止时间: 2005-12-15 至 2008-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/LP0562379
• 关键词: Physicochemical; Approach; Optimizing; Drug; Delivery

By applying modern techniques and a multidisciplinary approach, this research will develop an understanding of drug loading of BioSiliconTM at a molecular level. This novel class of nano-structured biomaterial has exciting potential for developing a range of controllable drug delivery systems. Existing medical applications of BioSilicon deliver only small molecules for very specialised uses. Current research has not focused on understanding the pore structure and how it can be adapted for special applications. Our research will create new drug delivery systems with many innovative applications in medical, veterinary and bio-diagnostics fields. The medical and socio-economic impacts will be internationally significant.

通过采用现代技术和多学科方法，这项研究将在分子水平上对生物智能的药物负载有所了解。这类新型的纳米结构生物材料具有开发一系列可控药物输送系统的令人兴奋的潜力。 Biosilicon的现有医疗应用仅提供非常专业用途的小分子。当前的研究并不集中于了解孔结构以及如何适应特殊应用。我们的研究将创建新的药物输送系统，并在医疗，兽医和生物诊断领域中进行许多创新的应用。医学和社会经济影响将在国际上具有重要意义。