Relationship between the morphological characteristics and the transmucosal gas exchange function in human middle ear cavity

人中耳腔形态特征与跨粘膜气体交换功能的关系

基本信息

批准号：
14571609
负责人：
YAMAMOTO Yutaka
金额：
$ 0.83万
依托单位：
NIIGATA UNIVERSITY
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (C)
财政年份：
2002
资助国家：
日本
起止时间：
2002 至 2003
项目状态：
已结题

来源：
https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-14571609/
关键词：
middle ear cavity transmucosal gas exchange nitrous oxide CT scan gas exchange surface area volume 経粘膜換 CTスキャ

项目摘要

There are few reports to evaluate the relationship between the function and morphological characteristic of middle ear cavity. In this research, the relationship between the transmucosal gas exchange function and the surface area and volume of middle ear cavity was investigated.1.Study to evaluate the relationship between surface area and volume in normal middle ear cavityMaterials were temporal bone CT scans of 23 patients with acoustic tumor without a past history of otitis media. The image data of CT scans were transported to a personal computer as DICOM formatted data, and analyzed by image analysis software. The perimeter and area of each air cell were measured, and then the surface area and volume of mastoid air cell system were calculated. The strong linear con-elation between the area and volume was confirmed.2.Study to evaluate the relationship between the morphological characteristics and the transmucosal gas exchange function in human middle ear cavityMaterials were 10 patients who undergo myringoplasty with dry tympanic membrane perforations without active inflammation in the middle ear cavity. At the time of operation under general anesthesia with the inhalation of nitrous oxide, increasing middle ear pressure caused by the diffusion of nitrous oxide was measured, and the gas exchange function was quantitatively evaluated. Surface area and volume of middle ear cavity were measured by CT scans. The strong correlations between the gas exchange ability and surface area, and the surface area and volume were confirmed.Human middle ear cavity had a large surface area corresponding to its large volume by having air cell systems, and the gas exchange function through the middle ear mucosa depended on the surface area. The morphological characteristic of middle ear cavity is of great advantage to regulating middle pressure by transmucosal gas exchange function.

几乎没有报道可以评估中耳腔功能和形态特征之间的关系。在这项研究中，研究了跨肿瘤气体交换功能与表面积和中耳腔体积之间的关系。1。研究评估正常中耳腔材料中表面积与体积之间的关系是23例没有过去耳炎培养基病史的声学肿瘤患者的颞骨CT扫描。将CT扫描的图像数据作为DICOM格式数据传输到个人计算机，并通过图像分析软件进行分析。测量每个空气电池的周长和面积，然后计算表面积和乳突空气电池系统的体积。证实了该面积和体积之间的强烈线性连接。在一般麻醉下运行时，测量了一氧化二氮的吸入，测量了由一氧化二氮扩散引起的中耳压力，并对气体交换功能进行了定量评估。通过CT扫描测量表面积和中耳腔体积。气体交换能力与表面积之间的强相关性以及表面积和体积得到了证实。人类中耳腔具有大型的表面积，通过具有空气电池系统来对应于其大容量，并且气体交换功能通过中耳粘膜取决于表面积。中耳腔的形态特征是通过跨肿瘤气体交换功能调节中压力的极佳优势。