Motor Evoked Potential by Magnetic Stimulation

磁刺激运动诱发电位

• 批准号: 63480330
• 负责人: KODAMA Namio
• 金额: $ 2.69万
• 依托单位: Fukushima Medical University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for General Scientific Research (B)
• 财政年份: 1990
• 资助国家: 日本
• 起止时间: 1990 至 无数据
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-63480330/
• 关键词: Magnetic stimulation; Motor evoked potential

Motor evoked potential (MEP) has been recorded by high voltage electrical stimulation. Magnetic stimulation, in contrast with electrical stimulation, is non invasive. But distribution of magnetic force generated by the coil has not been studied accurately.And then in dogs, MEP by transcranial magnetic stimulation is recorded from brachial muscle and epidural space at cervical level.Next, as clinical study, amplitude and latency of MEP recorded from the bilateral thiner muscle are investigated in the patients with hemiparesis.The following results are obtained.1 : Magnetic induction flux density is greater at the edge of the coil than center. 2 : In anesthesied dogs, MEP is recorded from the brachial muscle, which latency is about 6-8msec. And MEP recorded from epidural space consist of two negative peaks corresponding to the electrical stimulation. 3 : In the patients with hemiplegia, MEP is not recorded. In the patients with hemiparesis, MEP has a tendency to be low amplitude and prolongation of latency, but it is not possible to evaluate motor function precisely.Transcranial magnetic stimulation is non invasive. MEP by magnetic stimulation will be useful for investigation of motor function.

运动诱发电位（MEP）已通过高压电刺激记录下来。与电刺激相比，磁刺激是非侵入性的。但线圈产生的磁力分布尚未准确研究。然后在狗身上，从肱肌和颈部硬膜外腔记录经颅磁刺激的 MEP。接下来，作为临床研究，从对偏瘫患者双侧较薄的肌肉进行了研究，得到以下结果：1：线圈边缘的磁感应通密度大于中心。 2：在麻醉犬中，MEP 是从肱肌记录的，潜伏期约为 6-8 毫秒。从硬膜外腔记录的 MEP 由与电刺激相对应的两个负峰组成。 3：偏瘫患者不记录MEP。对于偏瘫患者，MEP有振幅低、潜伏期延长的倾向，但无法准确评估运动功能。经颅磁刺激是非侵入性的。磁刺激 MEP 将有助于研究运动功能。