Cell wall structure and dynamics in emerging fungal pathogens of crops

作物新兴真菌病原体的细胞壁结构和动态

• 批准号: DP160100309
• 负责人: Prof Vincent Bulone
• 金额: $ 47.76万
• 依托单位: The University of Adelaide
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2016
• 资助国家: 澳大利亚
• 起止时间: 2016-04-01 至 2019-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP160100309
• 关键词: Cell; wall; structure; dynamics; emerging

The project aims to understand the role of fungal cell wall biosynthetic enzymes in cell wall stability. The fungal cell wall is a dynamic structure whose composition constantly changes in response to biotic and abiotic stresses and at different developmental stages. The devastating fungal crop pathogen Fusarium graminearum is responsible for the head blight disease in cereals. The project aims to understand the molecular events that govern metabolism and dynamics of the cell wall of F. graminearum. The project also plans to characterise the molecular interactions involved in plant defence against fungal pathogens and fungal responses to plant immune factors called defensins. Expected long-term outcomes include the development of novel strategies for disease control and crop protection.

该项目旨在了解真菌细胞壁生物合成酶在细胞壁稳定性中的作用。真菌细胞壁是一种动态结构，其成分随着生物和非生物胁迫以及在不同的发育阶段而不断变化。毁灭性的作物真菌病原体禾谷镰刀菌 (Fusarium graminearum) 是造成谷物赤霉病的原因。该项目旨在了解控制禾谷镰刀菌细胞壁代谢和动力学的分子事件。该项目还计划表征植物针对真菌病原体的防御以及真菌对植物免疫因子（称为防御素）的反应所涉及的分子相互作用。预期的长期成果包括制定疾病控制和作物保护的新策略。