Interactions Between Bacteria of the Roseobacter Group and Marine Algae via Sulfur Metabolites (B07*)

玫瑰杆菌属细菌与海藻之间通过硫代谢物的相互作用 (B07*)

• 批准号: 397979925
• 金额: --
• 依托单位: Kekulé-Institut für Organische Chemie und Biochemie
• 依托单位国家: 德国
• 项目类别: CRC/Transregios
• 财政年份: 2018
• 资助国家: 德国
• 起止时间: 2017-12-31 至 2020-12-31
• 项目状态: 已结题
• 来源: https://gepris.dfg.de/gepris/projekt/397979925?language=en
• 关键词: Interactions; Between; Bacteria; Roseobacter; Group

During the third application period the interactions between bacteria of the Roseobacter group with other organisms via sulfur metabolites such as tropodithietic acid (TDA) and 2,3-dihydroxypropane-1-sulfonate (DHPS) will be studied as well as mechanisms of N-Acylhomoserine lactones (AHL) synthesis. Work on elucidating all enzymes in TDA biosynthesis will be completed, two further classes of DMSP lyases/hydrolases and enzymes of the DMSP demethylation pathway will be characterized and DHPS degradation studied in vitro.

在第三个应用期间，将研究玫瑰杆菌属细菌通过原二硫酸（TDA）和2,3-二羟基丙烷-1-磺酸盐（DHPS）等硫代谢物与其他生物体之间的相互作用，以及N-酰基高丝氨酸的机制内酯（AHL）的合成。阐明 TDA 生物合成中所有酶的工作将完成，另外两类 DMSP 裂解酶/水解酶和 DMSP 去甲基化途径的酶将被表征，并在体外研究 DHPS 降解。