MRI: Track 3 Acquisition of Helium Recovery Equipment to Establish a Sustainable NMR Facility at the University of Toledo

MRI：第 3 轨道采购氦回收设备，在托莱多大学建立可持续的 NMR 设施

• 批准号: 2320218
• 负责人: Yong-Wah Kim
• 金额: $ 32.3万
• 依托单位: University of Toledo
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-09-01 至 2026-08-31
• 项目状态: 未结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=2320218&HistoricalAwards=false
• 关键词: MRI; Track; Acquisition; Helium; Recovery

This award is jointly supported by the Major Research Instrumentation (MRI) and the Chemistry Research Instrumentation programs in response to the solicitation of proposals that promote the recovery, recycle, and/or reuse of helium initiated by the CHIPS and Science Act of 2022. The University of Toledo is acquiring a helium recovery system to capture and reliquefy helium from four NMR spectrometers which support the research of Professor Yong-Wah Kim along with colleague Jon Kirchhoff. This equipment supports research in the areas of synthetic chemistry, polymer chemistry, catalysis, and drug discovery. In general, Nuclear Magnetic Resonance (NMR) spectroscopy is one of the most powerful tools available to chemists for the elucidation of the structure of molecules. Using the intrinsic magnetic properties of atomic nuclei, it is used to identify unknown substances, to characterize specific arrangements of atoms within molecules, and to study the dynamics of interactions between molecules in solution or in the solid state. Access to state-of-the-art NMR spectrometers is essential to chemists who are carrying out frontier research. The superconducting magnets of these instruments rely on regular deliveries of liquid helium to maintain their operation. However, the instability in the helium supply due to global and national challenges jeopardizes research programs relying on NMR spectroscopy. A helium recovery system collects the helium boiloff from the superconducting magnets of NMR spectrometers and then reliquefies the helium for reuse. This equipment supports the educational, research, and teaching efforts at all levels in multiple departments as well as academic and industrial researchers throughout northwest Ohio. This award is aimed at supporting research and education at all levels. Specifically, this helium recovery system collects the helium boiloff for reliquefication and reuse from the superconducting magnets which sustains the operation of the institution’s four NMR spectrometers. The NMR instrumentation supported by this equipment enables numerous research projects including the rational design of transition metal catalysis for C-H activation and functionalization and the development of recyclable bio-based co-polyesters for packaging. The equipment sustains instrumentation which involves harnessing nitrogen-centered and transition metal complexes for the synthesis of nitrogen-containing heterocycles and the development of organometallic catalysts for green chemistry. Other research projects benefitting from this award include the study of nitric oxide release from neuroprotective nitric oxide mimetics and the development of inorganic and organometallic catalysts and reagents.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

该奖项由主要研究仪器 (MRI) 和化学研究仪器项目联合支持，以响应 2022 年《CHIPS 和科学法案》发起的促进氦气回收、再循环和/或再利用的提案征集。托莱多大学正在采购一套氦气回收系统，用于从四台核磁共振波谱仪中捕获并再液化氦气，该系统支持 Yong-Wah Kim 教授和同事 Jon Kirchhoff 的研究。该设备支持合成化学、聚合物化学、催化和药物发现领域的研究。总的来说，核磁共振 (NMR) 光谱是化学家阐明分子结构的最强大工具之一。原子核的固有磁性，它用于识别未知物质，表征分子内原子的特定排列，并研究溶液或固态中分子之间相互作用的动力学。艺术核磁共振光谱仪对于进行前沿研究的化学家来说至关重要，这些仪器的超导磁体依靠定期供应液氦来维持其运行，但是，由于全球和国家挑战而导致的氦供应不稳定危及了依赖核磁共振的研究项目。氦气回收系统从核磁共振波谱仪的超导磁体中收集氦气，然后将氦气重新液化以供重复使用。设备支持俄亥俄州西北部多个部门以及学术和工业研究人员的各级教育、研究和教学工作。具体而言，该氦气回收系统收集氦气蒸发。用于维持该机构的四台 NMR 波谱仪运行的超导磁体的再液化和再利用。该设备支持的 NMR 仪器可实现许多研究项目，包括合理设计用于 C-H 活化的过渡金属催化。用于包装的可回收生物基共聚酯的功能化和开发该设备支持利用氮中心和过渡金属配合物合成含氮杂环以及开发绿色化学有机金属催化剂的仪器。受益于该奖项的包括神经保护性一氧化氮模拟物释放一氧化氮的研究以及无机和有机金属催化剂和试剂的开发。授予 NSF 的法定使命，并通过评估反映使用基金会的智力优点和更广泛的影响审查标准，被认为值得支持。