Collaborative Research: Using the Physics of Living Systems Student Research Network to Transmit Techniques and Train Talent
合作研究:利用生命系统物理学学生研究网络传播技术和培养人才
基本信息
- 批准号:2310742
- 负责人:
- 金额:$ 44.97万
- 依托单位:
- 依托单位国家:美国
- 项目类别:Standard Grant
- 财政年份:2023
- 资助国家:美国
- 起止时间:2023-09-01 至 2026-08-31
- 项目状态:未结题
- 来源:
- 关键词:
项目摘要
The Physics of Living Systems (PoLS) is a diverse field and is composed of researchers and students from varied scientific backgrounds. No single institution can offer the breadth and depth of research and courses that both cover the relevant intellectual landscape and provide in-depth training for students. Such training is critical to create the next generation of researchers who can contribute to PoLS, with the ability to move between biology, physics, mathematics, and engineering. In addition, no single institution has the range of equipment needed to study PoLS on the enormous range of time and length scales encountered in biological systems. Finally, few single institutions can fruitfully integrate science and engineering to inspire biomedical, pharmaceutical, robotic, and prosthetic technologies that will result from basic PoLS research. This award’s activities will allow students to work across institutions and among various disciplines on living systems while maintaining the physics mindset (simplified systems, few parameters, predictive models) and developing new physics. The NSF Physics of Living Systems (PoLS) Student Research Network (SRN) strives to unite students and faculty working on the physics of living systems/biological physics at institutions ("nodes") within the US and internationally. This virtual network gives students at local nodes the ability to take advantage of global educational and research opportunities in PoLS. During the last period of funding members of the SRN continued to advance their respective PoLS programs and developed cohesive local communities. Students and faculty also participated in the SRN-wide annual meetings and activities at the American Physical Society (APS) March Meeting, the Biophysical Society (BPS) meeting, and other scientific meetings. With this award, the team of investigators will develop a focused set of activities that will generate significant interactions and exchange between students from different nodes and the POLS community. The primary activity of this award is to develop a set of student-led, hands-on, short courses at node sites ("Hands-On PoLS Summer Schools"). Short courses will be held for a week each summer at each node and will train SRN students with both specialized and general techniques useful across PoLS disciplines. Each node will develop a suite of summer-school courses with themes that span different research interests and capabilities (e.g., microscopy, robophysics, image analysis), targeted for students from all nodes and other institutions in the SRN. This award will aid development of and sponsor travel support to the short courses. These activities will be augmented by research exchange visits among nodes within this proposal as well as in the broader iPOLS SRN. This award will also sponsor travel to diverse scientific meetings important to the student's specific research areas as well as to gain a broader perspective on PoLS. While this SRN seek to maintain ties to and cultivate insights from biology, medicine, and other relevant disciplines, a strong SRN will help demonstrate that fundamental living systems research has been and will continue to be done by physicists. The SRN students will be among the next generation of researchers and educators who will continue this trajectory. PoLS topics form natural recruitment vehicles for students into physics as well as interest the broader public, workforce, and administration. The SRN activities and eager students will leverage these strengths, for example disseminating such ideas to K-12 institutions, thereby increasing the flow of students into PoLS in universities. This award will promote to synergize these activities by running seminars showcasing SRN alumni with non-academic careers, thereby broadening the pool of researchers with the PoLS mindset. Investigators in this project will continue their commercialization efforts of technologies resulting from their research, adding this aspect to the US PoLS "ecosystem".This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.
生活系统物理学(POLS)是一个不同的领域,由不同科学背景的研究人员和学生组成。没有一个机构可以提供研究和课程的广度和深度,既涵盖相关的智力景观,又为学生提供深入的培训。这种培训对于创建可以为POL做出贡献的下一代研究人员至关重要,并具有在生物学,物理,数学和工程学之间移动的能力。此外,没有一个机构拥有研究POR在生物系统中遇到的时间和长度范围增强的范围范围所需的设备范围。最后,很少有单一机构能够完全整合科学和工程学,以激发基本POLS研究将导致的生物医学,制药,机器人和假肢技术。该奖项的活动将使学生能够跨机构和各个学科的生活系统工作,同时保持物理心态(简化系统,很少的参数,预测模型)和开发新物理学。 NSF的生活系统物理学(POLS)学生研究网络(SRN)致力于在美国和国际上从事机构(“节点”)的生活系统/生物物理物理学的团结学生和教职员工。这个虚拟网络使本地节点的学生能够利用POLS中的全球教育和研究机会。在筹集资金的最后一个阶段,SRN继续推进各自的POLS计划并开发了凝聚力的当地社区。学生和教职员工还参加了美国物理学会(APS)3月会议,生物物理学会(BPS)会议和其他科学会议的范围内的年度会议和活动。有了这个奖项,调查人员团队将开发一系列重点的活动,这些活动将产生来自不同节点和POLS社区的学生之间的重大互动和交流。该奖项的主要活动是在节点网站(“动手pols暑期学校”)开发一套由学生主导的,动手的短课程。每个夏天将在每个节点上举行一个星期的短课程,并将培训SRN学生在POLS学科中使用专门和一般技术的SRN学生。每个节点将开发一套夏季课程的套件,其主题涵盖了不同的研究兴趣和能力(例如显微镜,rounysics,图像分析),该课程针对来自SRN的所有节点和其他机构的学生。该奖项将在短期课程中听到和赞助商的旅行支持。这些活动将通过该提案和更广泛的IPOLS SRN中的节点之间的研究交流访问来增强。该奖项还将参加对学生特定研究领域重要的多种科学会议,并对POLS的更广泛看法。尽管该SRN试图保持与生物学,医学和其他相关学科的见解,但强大的SRN将有助于证明基本的生活系统研究已经并且将继续由物理学家完成。 SRN学生将成为下一代研究人员和教育者之一,他们的主题为学生构成了天然招聘工具,并有趣的是,更广泛的公众,劳动力和行政管理。 SRN的活动和渴望的学生将利用这些优势,例如向K-12机构传播此类想法,从而将学生的流动增加到大学的pol。该奖项将促进通过非学术职业向SRN校友展示SRN校友来协同这些活动的促进,从而通过POLS心态扩大了研究人员的群体。该项目中的研究人员将继续他们的研究对技术的商业化工作,并将这一方面添加到美国的“生态系统”中。本奖反映了NSF的法定任务,并通过使用该基金会的知识分子优点和更广泛的影响来评估NSF的法定任务,并被认为是宝贵的支持。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Arpita Upadhyaya其他文献
Mechanical regulation of cytoskeletal dynamics and function in cytotoxic T lymphocytes
- DOI:
10.1016/j.bpj.2023.11.882 - 发表时间:
2024-02-08 - 期刊:
- 影响因子:
- 作者:
Aashli Pathni;Vishavdeep Vashisht;Lei Li;Neha Narayan;Zhengguo Xiao;Arpita Upadhyaya - 通讯作者:
Arpita Upadhyaya
Structure and Mechanical Properties of Actin Networks Crosslinked with Mutually Interacting Crosslinkers
- DOI:
10.1016/j.bpj.2010.12.3428 - 发表时间:
2011-02-02 - 期刊:
- 影响因子:
- 作者:
Brian Grooman;Ikoku Fujiwara;Carol Otey;Arpita Upadhyaya - 通讯作者:
Arpita Upadhyaya
Cytoskeletal Dynamics and Mechanosensing in Immune Cells
- DOI:
10.1016/j.bpj.2020.11.904 - 发表时间:
2021-02-12 - 期刊:
- 影响因子:
- 作者:
Arpita Upadhyaya - 通讯作者:
Arpita Upadhyaya
Spreading Dynamics and Oscillatory Membrane Behavior of B Lymphocytes
- DOI:
10.1016/j.bpj.2010.12.1872 - 发表时间:
2011-02-02 - 期刊:
- 影响因子:
- 作者:
Christina Ketchum;Chaohong Liu;Wenxia Song;Arpita Upadhyaya - 通讯作者:
Arpita Upadhyaya
Rapid Treadmilling and Myosin Motors Synergistically Induce Formation of Ring-Like Actomyosin Architectures and Cortexes
- DOI:
10.1016/j.bpj.2018.11.1371 - 发表时间:
2019-02-15 - 期刊:
- 影响因子:
- 作者:
Qin Ni;Arpita Upadhyaya;Garegin A. Papoian - 通讯作者:
Garegin A. Papoian
Arpita Upadhyaya的其他文献
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{{ truncateString('Arpita Upadhyaya', 18)}}的其他基金
Transitions: Mechanical Regulation of Transcription Factor Dynamics, Chromatin Accessibility and Gene Expression
转变:转录因子动力学、染色质可及性和基因表达的机械调节
- 批准号:
2132922 - 财政年份:2022
- 资助金额:
$ 44.97万 - 项目类别:
Standard Grant
Investigating How Active Fluctuations Drive Immune Receptor Dynamics and Signaling
研究主动波动如何驱动免疫受体动态和信号传导
- 批准号:
1915534 - 财政年份:2020
- 资助金额:
$ 44.97万 - 项目类别:
Continuing Grant
Collaborative Research: Formation of a High Flux Student Research Network (HF-SRN) as a Laboratory for Enhancing Interaction in the PoLS SRN
合作研究:建立高通量学生研究网络(HF-SRN)作为增强 PoLS SRN 互动的实验室
- 批准号:
1806903 - 财政年份:2018
- 资助金额:
$ 44.97万 - 项目类别:
Continuing Grant
Mechanisms of Immune Cell Response to Mechanical Load
免疫细胞对机械负荷的反应机制
- 批准号:
1563355 - 财政年份:2016
- 资助金额:
$ 44.97万 - 项目类别:
Standard Grant
Physics of Centrosome Reorientation during Signaling Activation in Immune Cells
免疫细胞信号激活过程中中心体重新定向的物理学
- 批准号:
1607645 - 财政年份:2016
- 资助金额:
$ 44.97万 - 项目类别:
Continuing Grant
Physical Aspects of Lymphocyte Activation
淋巴细胞激活的物理方面
- 批准号:
1206060 - 财政年份:2012
- 资助金额:
$ 44.97万 - 项目类别:
Continuing Grant
Collaborative Research: Regulation of Cellular Mechanics by Crosslinked Actin Networks - Role of Palladin and Alpha-actinin
合作研究:交联肌动蛋白网络调节细胞力学 - Palladin 和 α-肌动蛋白的作用
- 批准号:
1121710 - 财政年份:2011
- 资助金额:
$ 44.97万 - 项目类别:
Continuing Grant
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