RoL: FELS: EAGER: Landscape Phenomics: Predicting vulnerability to climate variation by linking environmental heterogeneity to genetic and phenotypic variation

RoL：FELS：EAGER：景观表型组学：通过将环境异质性与遗传和表型变异联系起来预测气候变化的脆弱性

• 批准号: 1838282
• 负责人: Chris Funk
• 金额: $ 30万
• 依托单位: Colorado State University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-10-01 至 2023-03-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1838282&HistoricalAwards=false
• 关键词: RoL; FELS; EAGER; Landscape; Phenomics

Biodiversity is critically important, however unprecedented losses are occurring in response to environmental change and human development of the planet. Since many species have survived past and present changes, understanding how they do so can provide clues for conserving biodiversity. This project seeks to address this question by evaluating different factors that contribute to a species' survival within its natural range. The research team will focus on the tailed frog, which lives only in cold, fast-flowing mountain streams in the U.S. Pacific Northwest. Within this region, many populations of frogs live in low elevation habitats that are warmer than high elevation habitats. These populations are likely to be the first to experience temperatures higher than what tailed frogs can tolerate as climates warm. It is possible, however, that frogs from these populations may also be able to tolerate warmer temperatures relative to those that live only in colder, high-elevation streams. This project will examine the implications for how tailed frogs or similar species might survive in the face changes in temperature. Uncovering these rules for how species may persist requires understanding how differences in the environment affect thermal tolerance and other traits that can allow species to survive as conditions are altered over time. This project will provide research training and mentoring for a postdoctoral scholar, and graduate and undergraduate students.The researchers will uncover rules for spatial patterns of vulnerability using a four-pronged integrative framework. This research links environmental heterogeneity to genetic and phenotypic variation in resilience traits. First, the study will characterize variation in the thermal environment and food resources in tailed frog streams. Second, it will test the effects of landscape heterogeneity on genome-wide variation and microevolutionary processes (selection, drift, and gene flow) using a landscape genomics approach. Third, it will estimate the contributions of genetics and the environment in generating variation in key resilience traits related to thermal performance using quantitative genetics, a genome-wide association study, and acclimation experiments. Finally, they will predict current and future temperature tolerance and population vulnerability by modeling changes in stream temperature, food resources, traits, and population responses.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

生物多样性至关重要，但由于环境变化和地球人类发展，生物多样性正在发生前所未有的损失。由于许多物种在过去和现在的变化中幸存下来，了解它们是如何生存的可以为保护生物多样性提供线索。该项目旨在通过评估有助于物种在其自然范围内生存的不同因素来解决这个问题。研究小组将重点关注尾蛙，它只生活在美国太平洋西北部寒冷、湍急的山涧中。在该地区，许多青蛙种群生活在比高海拔栖息地温暖的低海拔栖息地。随着气候变暖，这些种群可能会首先经历高于尾蛙所能忍受的温度。然而，与仅生活在寒冷、高海拔溪流中的青蛙相比，这些种群的青蛙也可能能够忍受更高的温度。该项目将研究尾蛙或类似物种如何在温度变化中生存的影响。要揭示物种如何持续存在的规则，需要了解环境差异如何影响耐热性和其他特征，这些特征可以使物种在条件随时间变化时生存。该项目将为博士后学者、研究生和本科生提供研究培训和指导。研究人员将利用四管齐下的综合框架揭示脆弱性空间模式的规则。这项研究将环境异质性与复原力特征的遗传和表型变异联系起来。首先，该研究将描述尾蛙溪流中热环境和食物资源的变化。其次，它将使用景观基因组学方法测试景观异质性对全基因组变异和微进化过程（选择、漂移和基因流）的影响。第三，它将利用定量遗传学、全基因组关联研究和驯化实验来估计遗传学和环境在产生与热性能相关的关键弹性特征变异方面的贡献。最后，他们将通过对溪流温度、食物资源、性状和种群反应的变化进行建模来预测当前和未来的温度耐受性和种群脆弱性。该奖项反映了 NSF 的法定使命，并通过使用基金会的智力优势和能力进行评估，被认为值得支持。更广泛的影响审查标准。

项目成果

Linking evolutionary potential to extinction risk: applications and future directions

• DOI: 10.1002/fee.2552
• 发表时间: 2022-08-17
• 期刊: FRONTIERS IN ECOLOGY AND THE ENVIRONMENT
• 影响因子: 10.3
• 作者: Forester, Brenna R.;Beever, Erik A.;Funk, W. Chris
• 通讯作者: Funk, W. Chris

Linking critical thermal maximum to mortality from thermal stress in a cold-water frog

将冷水蛙的临界热最大值与热应激死亡率联系起来

• DOI: 10.1098/rsbl.2023.0106
• 发表时间: 2023
• 期刊: Biology Letters
• 影响因子: 3.3
• 作者: Cicchino, Amanda S.;Ghalambor, Cameron K.;Funk, W. Chris
• 通讯作者: Funk, W. Chris

Multi‐scale relationships in thermal limits within and between two cold‐water frog species uncover different trends in physiological vulnerability

两种冷水蛙物种内部和之间热极限的多尺度关系揭示了生理脆弱性的不同趋势

• DOI: 10.1111/fwb.14102
• 发表时间: 2023
• 期刊: Freshwater Biology
• 影响因子: 2.7
• 作者: Cicchino, Amanda S.;Shah, Alisha A.;Forester, Brenna R.;Dunham, Jason B.;Ghalambor, Cameron K.;Funk, W. Chris
• 通讯作者: Funk, W. Chris

The crucial role of genome-wide genetic variation in conservation

• DOI: 10.1073/pnas.2104642118
• 发表时间: 2021-11-30
• 期刊: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
• 影响因子: 11.1
• 作者: Kardos, Marty;Armstrong, Ellie E.;Funk, W. Chris
• 通讯作者: Funk, W. Chris