MRI: Acquisition of a Rheometer for Research and Research Training in Science and Engineering at CSULA

MRI：购买流变仪用于 CSULA 科学与工程研究和研究培训

• 批准号: 1727015
• 负责人: Yong Ba
• 金额: $ 27.16万
• 依托单位: California State L A University Auxiliary Services Inc.
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-10-01 至 2021-09-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1727015&HistoricalAwards=false
• 关键词: MRI; Acquisition; Rheometer; Research; Training

This award from the Major Research Instrumentation program supports California State University Los Angeles with the acquisition of Rheometer. The instrument supports studies of the rheological properties of fluidic substances in five different areas. These are (1) the study of the molecular mechanism of mucoadhesion of the sol-gel two-phase co-hydrogel system for potential biomedical applications; (2) the study of the Ice Binding protein enhanced deicing/anti-icing fluids for aviation and other industrial applications; (3) the characterization of the dynamics of partially saturated and heterogeneous granular materials; (4) the study of the rheological properties of chitosan-methyl cellulose composite film forming solutions; and (5) the study of the rheological properties of non-starch polysaccharides from dry bean seeds. The rheometer is also used for research training of a diverse STEM workforce through laboratory experiments.The acquisition of a Rheometer enables research, education and training on the rheological properties of fluidic substances across three colleges at California State University Los Angeles. The research includes the study of the molecular mechanism of mucoadhesion of the sol-gel two-phase co-hydrogel system for potential biomedical applications. Using the combined methods of rheometry and rheological Nuclear Magnetic Resonance(Rheo-NMR) to correlate the viscoelastic property of the co-hydrogel and mucus system with the molecular information including molecular dynamics, interaction and orientation. A second project combines methods of rheometer and Rheo-NMR to study the Ice Binding Protein (IBP) in enhanced deicing/anti-icing fluids for aviation and other industrial applications. The third project combines rheological experiment, modeling, and simulation to characterize the mechanics of anisotropic and cohesive granular materials for off-road mobility. The fourth project studies the rheological properties of chitosan-methyl cellulose composite film forming solutions. The fifth project investigates the rheological properties of non-starch polysaccharides from dry bean seeds. This instrument is also used for research and training of a divers student population through laboratory experiments.

该奖项来自主要研究仪器计划，支持加州州立大学洛杉矶分校收购流变仪。该仪器支持五个不同领域流体物质流变特性的研究。这些是（1）溶胶-凝胶两相共水凝胶系统粘膜粘附分子机制的研究，用于潜在的生物医学应用； （2）用于航空和其他工业应用的冰结合蛋白增强除冰/防冰液的研究； (3) 部分饱和和非均质颗粒材料的动力学表征； (4)壳聚糖-甲基纤维素复合成膜液流变性能的研究； (5)干豆籽非淀粉多糖流变特性的研究。该流变仪还用于通过实验室实验对多样化的 STEM 人员进行研究培训。购买流变仪可以在加州州立大学洛杉矶分校的三个学院进行流体物质流变特性的研究、教育和培训。该研究包括研究溶胶-凝胶两相共水凝胶系统粘膜粘附的分子机制，以用于潜在的生物医学应用。利用流变测定法和流变核磁共振（Rheo-NMR）相结合的方法，将共水凝胶和粘液系统的粘弹性特性与分子动力学、相互作用和取向等分子信息相关联。第二个项目结合了流变仪和流变核磁共振方法，研究航空和其他工业应用的增强型除冰/防冰液中的冰结合蛋白 (IBP)。第三个项目结合了流变实验、建模和模拟，以表征越野机动性的各向异性和粘性颗粒材料的力学特性。第四个项目研究壳聚糖-甲基纤维素复合成膜溶液的流变特性。第五个项目研究干豆种子中非淀粉多糖的流变特性。该仪器还用于通过实验室实验对不同学生群体进行研究和培训。

项目成果

Mucoadhesive and Rheological Studies on the Co-Hydrogel Systems of Poly(Ethylene Glycol) Copolymers with Fluoroalkyl and Poly(Acrylic Acid)

聚乙二醇与氟代烷基和聚丙烯酸共水凝胶体系的粘膜粘附和流变学研究

• DOI: 10.3390/polym13121956
• 发表时间: 2021-06-12
• 期刊: Polymers
• 影响因子: 5
• 作者: Sun Y;Perez AF;Cardoza IL;Baluyot-Reyes N;Ba Y
• 通讯作者: Ba Y