MRI: Acquisition of a Rheometer for Interdisciplinary Material Science Research and Training of Undergraduate Researchers

MRI：购买流变仪用于跨学科材料科学研究和本科研究人员培训

• 批准号: 1919429
• 负责人: Ryan McGorty
• 金额: $ 26.38万
• 依托单位: University of San Diego
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-09-15 至 2023-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1919429&HistoricalAwards=false
• 关键词: MRI; Acquisition; Rheometer; Interdisciplinary; Material

This award, from the Major Research Instrumentation program, supports the University of San Diego's acquisition of a rheometer. Rheometers are routinely used to study the flow and deformation of soft materials (for example, gels) as a function of applied force and time. Rheometers measure properties such as viscosity, which is a measure of resistance to flow. For instance, water flows easier than honey, so it has a lower viscosity. Viscoelastic materials are those that exhibit both viscous and elastic characteristics under deformation. The rheometer to be acquired is capable of precisely controlling sample temperature, and it also provides direct microscopic visualization of samples under flow. The rheometer also is equipped with tools to measure the tensile and bending strength of solid materials. This instrument will enable the University of San Diego faculty to conduct cutting-edge research on topics related to the behavior of biopolymers (for example, DNA solutions) and antibacterial materials. The rheometer will be used to provide hands-on training of undergraduates across different disciplines such as bioengineering and physics. The instrument also will enable the development of a new interdisciplinary course on biomaterials.A state-of-the-art rheometer equipped with multiple accessories will accommodate diverse research and teaching needs at the University of San Diego, a primarily undergraduate teaching institution. This instrument will significantly advance four specific projects at the University of San Diego. First, it will be used to answer questions on how fluid-fluid phase separation is influenced by shear. Second, it will measure the mechanical properties of starch hydrogels which are used to deliver antimicrobial agents. Third, it will determine how the rheological properties of seawater are altered by mucous secretions and aggregates of microorganisms. Finally, it will measure the viscoelastic properties of biomaterials including cytoskeletal networks and entangled DNA solutions. These main projects, as well as others at the University of San Diego and at neighboring institutions, will be advanced substantially by this state-of-the-art rheometer.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

该奖项来自主要研究仪器计划，支持圣地亚哥大学购买流变仪。流变仪通常用于研究软材料（例如凝胶）的流动和变形随施加的力和时间的变化。流变仪测量粘度等特性，粘度是流动阻力的量度。例如，水比蜂蜜更容易流动，因此它的粘度较低。粘弹性材料是在变形下同时表现出粘性和弹性特性的材料。待获得的流变仪能够精确控制样品温度，并且还提供流动下样品的直接显微可视化。 流变仪还配备了测量固体材料拉伸和弯曲强度的工具。该仪器将使圣地亚哥大学的教师能够对与生物聚合物（例如 DNA 溶液）和抗菌材料的行为相关的主题进行前沿研究。该流变仪将用于为生物工程和物理学等不同学科的本科生提供实践培训。该仪器还将支持开发新的生物材料跨学科课程。配备多种附件的最先进的流变仪将满足圣地亚哥大学（主要是本科教学机构）的不同研究和教学需求。该工具将显着推进圣地亚哥大学的四个具体项目。首先，它将用于回答有关剪切如何影响流体-流体相分离的问题。其次，它将测量用于传递抗菌剂的淀粉水凝胶的机械性能。第三，它将确定粘液分泌物和微生物聚集体如何改变海水的流变特性。最后，它将测量生物材料的粘弹性特性，包括细胞骨架网络和缠结的 DNA 溶液。这些主要项目以及圣地亚哥大学和邻近机构的其他项目将通过这款最先进的流变仪大幅推进。该奖项反映了 NSF 的法定使命，并通过使用基金会的智力价值和更广泛的影响审查标准。

项目成果

Shear-induced vorticity aligned flocs in a temperature responsive colloid-polymer mixture

温度响应胶体聚合物混合物中剪切引起的涡度排列絮凝体

• DOI: 10.3389/fphy.2022.955006
• 发表时间: 2022-09-15
• 期刊: Energy Conversion and Management
• 影响因子: 10.4
• 作者: Ryle Rel;D. Terwilliger;R. McGorty
• 通讯作者: R. McGorty

Core–shell droplets and microcapsules formed through liquid–liquid phase separation of a colloid–polymer mixture

通过胶体-聚合物混合物的液-液相分离形成核-壳液滴和微胶囊

• DOI: 10.1039/d1sm01091c
• 发表时间: 2021-09
• 期刊: Soft Matter
• 影响因子: 3.4
• 作者: Dang, Steven;Brady, John;Rel, Ryle;Surineni, Sreenidhi;O’Shaughnessy, Conor;McGorty, Ryan
• 通讯作者: McGorty, Ryan

Cooperative Rheological State‐Switching of Enzymatically‐Driven Composites of Circular DNA And Dextran

协同流变状态——酶驱动的环状 DNA 和葡聚糖复合物的切换

• DOI: 10.1002/adma.202305824
• 发表时间: 2023-10
• 期刊: Advanced Materials
• 影响因子: 29.4
• 作者: Marfai, Juexin;McGorty, Ryan J.;Robertson‐Anderson, Rae M.
• 通讯作者: Robertson‐Anderson, Rae M.

DNA topology dictates emergent bulk elasticity and hindered macromolecular diffusion in DNA-dextran composites

DNA 拓扑结构决定了 DNA-葡聚糖复合材料中出现的体积弹性和受阻的大分子扩散

• DOI: 10.1122/8.0000447
• 发表时间: 2022-07-01
• 期刊: Journal of Rheology
• 影响因子: 3.3
• 作者: Pawan Khanal;K. Peddireddy;Juexin Marfai;R. McGorty;R. Robertson
• 通讯作者: R. Robertson