MRI: Acquisition of a cryoprobe- and autosampler-equipped AVANCE III 500 MHz solution NMR

MRI：采集配备冷冻探头和自动进样器的 AVANCE III 500 MHz 解决方案 NMR

• 批准号: 1532078
• 负责人: Valerie Copie
• 金额: $ 50.41万
• 依托单位: Montana State University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-08-15 至 2018-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1532078&HistoricalAwards=false
• 关键词: MRI; Acquisition; cryoprobe; autosampler; equipped

An award is made to Montana State University to purchase a Bruker AVANCE III 500 MHz NMR spectrometer equipped with a sensitivity-enhanced Prodigy TM broadband cryoprobe. The new instrument will enhance research and education at all levels. It will strongly benefit student education at both the graduate and the undergraduate level by enabling student training in new, powerful small molecule NMR analytical techniques. MSU provides direct, hands-on training to students in state-of-the-art instrumentation, which is taught in venues ranging from summer undergraduate research programs to sophomore organic laboratory courses to graduate level instructional programs. The new AVANCE III 500 NMR with its enhanced capabilities will also enable them to enhance participation of minority Native American students through remote instrument access that will provide NMR spectra to students enrolled in sciences classes at remote Montana Tribal Colleges and at other small colleges across the state.The cryoprobe-equipped AVANCE III 500 NMR will allow researchers to use NMR for chemical structure elucidation and the global analysis of small molecule metabolites (e.g. metabolomics) research, will enhance usage by permitting higher throughput data collection, and will facilitate studies in applications with inherently low selectivity. In addition, the new instrument will be the workhorse NMR spectrometer for the university and will greatly expand Montana State University's NMR research capabilities for acquisition of multidimensional (1D, 2D, 3D/nD) heteronuclear (1H, 13C, 15N, 31P) NMR spectra of small molecules. The new instrumentation, which will replace MSU's aged 500 NMR spectrometer, will boost research productivity and student education. The new instrument is absolutely essential to maintain the university's research productivity, educational quality, and outreach mission, and for successful recruitment of new faculty.

向蒙大拿州立大学颁发了奖励，购买了配备有灵敏度增强的神童TM宽带冰可的Bruker Avance III 500 MHz NMR光谱仪。新工具将在各个层面增强研究和教育。通过为新的，强大的小分子NMR分析技术培训学生培训，它将在研究生和本科层面上有力地受益。 MSU为最先进的仪器的学生提供直接的动手培训，该培训是在夏季本科研究计划到大二学生有机实验室课程到研究生级教学课程的场所教授的。新的Avance III 500 NMR具有增强的功能，还将使他们能够通过远程仪器访问来增强少数美洲原住民学生的参与，这将为偏远的蒙大拿州部落学院的科学课程提供NMR Spectra，并在全州其他小型学院的其他小型学院中提供NMR Spectra。代谢产物（例如代谢组学）研究将通过允许较高的吞吐量数据收集来增强使用，并促进对具有固有较低选择性的应用的研究。此外，新仪器将是该大学的主力NMR光谱仪，并将大大扩展蒙大拿州立大学的NMR NMR研究能力，用于获取多维（1D，2D，2D，3D/ND）异核（1H，1H，13C，13C，13C，15N，31p）NMR小分子的NMR光谱。新的仪器将取代MSU年龄500 NMR光谱仪，将提高研究生产力和学生教育。新工具对于维持大学的研究生产力，教育质量和外展任务以及成功招募新教师绝对至关重要。